You are currently viewing a beta version of our website. If you spot anything unusual, kindly let us know.
Altmetrics
Downloads
135
Views
57
Comments
0
This version is not peer-reviewed
Medium | NaCl gradient (g·L-1) | NaNO3 gradient (g·L-1) | |
---|---|---|---|
Control | BBM | 0.025 | 0.25 |
High salinity | BBM | 5, 7.5, 10, 12.5 | 0.25 |
Low nitrogen | nitrogen-deficient BBM | 0.025 | 0, 0.032, 0.065, 0.13 |
Metabolite | KEGG code |
Fold change | Metabolite | KEGG code |
Fold change | ||
---|---|---|---|---|---|---|---|
HS vs CK | LN vs CK | HS vs CK | LN vs CK | ||||
N2,N2-Dimethylguanosine | NA | 0.35 | 0.33 | 6-Hydroxynicotinic acid | C01020 | 0.81 | 1.77 |
AMP | C00020 | 0.19 | 0.47 | N6-Acetyl-L-lysine | C02727 | 0.72 | 0.42 |
Glycerophosphocholine | C00670 | 0.73 | 0.57 | ATP | C00002 | 5.11 | 1.48 |
Glyceric acid | C00258 | 0.35 | 0.23 | L-Lactic acid | C01432 | 0.85 | 0.47 |
5-hydroxy-Tryptophan | C01017 | 0.15 | 0.46 | NAD | C00003 | 1.32 | 0.36 |
Nicotinic acid | C00253 | 0.43 | 0.48 | N-Acetyl-D-glucosamine | C00140 | 0.97 | 0.49 |
L-Aspartate | C00049 | 4.14 | 2.42 | NAAD | C00857 | 1.30 | 0.35 |
L-Proline | C00148 | 0.85 | 0.52 | N-Acetylcadaverine | NA | 1.85 | 0.69 |
Thymine | C00178 | 4.62 | 2.11 | dAMP | C00360 | 0.34 | 0.76 |
L-Carnitine | C00318 | 0.39 | 0.84 | Malate | C00711 | 0.92 | 0.34 |
UMP | C00105 | 0.31 | 0.41 | N-Carbamoyl-L-aspartic acid | C00438 | 1.99 | 0.63 |
cAMP | C00575 | 0.40 | 0.21 | Guanosine | C00387 | 1.75 | 0.38 |
ℽ-Glutamyl-L-methionine | NA | 3.09 | 1.17 | L-Asparagine | C00152 | 0.96 | 0.56 |
GDP | C00035 | 1.99 | 3.12 | Cytidine | C00475 | 0.72 | 0.75 |
Nicotinamide | C00153 | 1.80 | 1.53 | Arginine | C03406 | 0.57 | 0.25 |
Dimethylglycine | C01026 | 0.53 | 0.97 | Sucrose | C00089 | 1.17 | 0.53 |
2'-O-methyladenosine | C04779 | 0.71 | 0.35 | Orotic acid | C00295 | 0.26 | 0.67 |
ℽ -L-Glutamyl-L-phenylalanine | NA | 1.00 | 8.80 | Allantoic acid | C00499 | 0.31 | 0.50 |
5'-Deoxyadenosine | C05198 | 0.78 | 0.06 | L-Citrulline | C00327 | 2.35 | 0.52 |
5-Aminopentanoic acid | C00431 | 0.58 | 0.68 | Flavone | C15608 | 0.46 | 1.23 |
L-Tyrosine | C00082 | 4.51 | 0.80 | 7-methylguanosine | NA | 1.13 | 0.39 |
Pantothenic acid | C00864 | 0.88 | 0.44 | Riboflavin | C00255 | 0.72 | 1.12 |
L-Pipecolic acid | C00408 | 2.92 | 1.44 | FAD | C00016 | 1.24 | 0.45 |
Deoxycytidine | C00881 | 1.50 | 2.15 | cis-4-Hydroxy-D-proline | C03440 | 0.20 | 0.08 |
N-Acetylglutamine | NA | 1.97 | 1.42 | NADP | C00006 | 4.32 | 0.54 |
CMP | C00055 | 0.63 | 0.43 | Biopterin | C06313 | 0.36 | 1.29 |
Tryptamine | C00398 | 0.51 | 0.42 | L-Glutamate | C00025 | 1.05 | 0.40 |
Choline | C00114 | 0.50 | 1.03 | L-Homoserine | C00263 | 1.19 | 0.60 |
CDPcholine | C00307 | 0.49 | 0.38 | Hypoxanthine | C00262 | 0.46 | 1.30 |
Glycerol3P | C00093 | 0.37 | 0.38 | Pyridoxal | C00250 | 1.06 | 0.70 |
cis-Aconitate | C00417 | 1.97 | 2.78 | 2,3-Dihydroxybenzoic acid | C00196 | 1.34 | 0.25 |
Nicotinamide ribotide | C00455 | 3.47 | 3.62 | Cholesterol sulfate | C18043 | 1.39 | 1.56 |
Adenine | C00147 | 0.99 | 3.87 | N-Formylmethionine | C03145 | 1.62 | 0.18 |
N-Acetyl-L-alanine | NA | 0.38 | 0.31 | Glycyl-L-leucine | C02155 | 0.62 | 1.11 |
Xanthosine | C01762 | 0.51 | 0.36 | L-Valine | C00183 | 1.32 | 0.46 |
Deoxyguanosine | C00330 | 2.02 | 0.83 | 4-Guanidinobutyric acid | C01035 | 0.70 | 0.94 |
D-Neopterin | C05926 | 2.44 | 0.37 | FMN | C00061 | 1.60 | 0.94 |
Succinate | C00042 | 0.66 | 0.31 | Glutathione disulfide | C00127 | 1.85 | 0.66 |
O-Succinyl-L-homoserine | C01118 | 0.58 | 0.09 | Urocanic acid | C00785 | 0.59 | 0.59 |
Uric acid | C00366 | 1.18 | 1.41 | L-Methionine | C00073 | 1.39 | 0.23 |
N6-methyladenosine | NA | 0.75 | 0.24 | 2-keto-D-Gluconic acid | C06473 | 1.33 | 0.29 |
D-glucosamine 1-phosphate | C06156 | 0.48 | 0.32 | L-Homocysteic acid | C16511 | 1.18 | 0.64 |
Isobutyryl-CoA | C00630 | 7.57 | 0.92 | dTMP | C00364 | 0.56 | 1.20 |
DHAP | C00111 | 0.31 | 0.26 | Inosine | C00294 | 1.01 | 0.25 |
Thiamine | C00378 | 14.25 | 101.38 | L-Serine | C00065 | 1.23 | 0.40 |
GABA | C00334 | 1.84 | 1.16 | IMP | C00130 | 0.30 | 2.96 |
GDP-L-fucose | C00325 | 0.50 | 0.28 | L-2-Aminoadipic acid | C00956 | 1.13 | 0.78 |
Phenyllactic acid | C05607 | 3.24 | 0.62 | dGMP | C00362 | 0.42 | 2.51 |
D-Glucose-6-phosphate | C00092 | 0.77 | 0.42 | S-Adenosylhomocysteine | C00021 | 1.09 | 0.11 |
Glycine | C00037 | 2.16 | 0.41 | N4-Acetylcytidine | NA | 0.51 | 1.81 |
Creatine | C00300 | 1.26 | 1.12 | UDP-D-Glucuronate | C00167 | 2.13 | 0.27 |
1-Methylxanthine | C16358 | 0.61 | 0.16 | UDP -Glucose | C00029 | 1.70 | 0.90 |
Deoxyinosine | C05512 | 1.64 | 0.73 | L-Kynurenine | C00328 | 0.97 | 0.37 |
Dephospho-CoA | C00882 | 22.19 | 1.84 | N-Acetyl-L-phenylalanine | C03519 | 1.44 | 0.35 |
β-Hydroxybutyric acid | C01089 | 1.65 | 0.46 | L-Leucine | C00123 | 0.64 | 0.52 |
TPP | C00068 | 4.57 | 1.54 | L-Phenylalanine | C00079 | 0.95 | 0.65 |
ℽ -L-Glutamyl-L-valine | NA | 0.82 | 2.99 | taurine | C00245 | 1.13 | 0.24 |
Adenosine | C00212 | 1.13 | 0.33 | Acetyl-DL-Leucine | NA | 1.23 | 0.37 |
Phosphoenolpyruvate | C00074 | 0.77 | 0.35 | dCMP | C00239 | 0.44 | 1.32 |
L-2-Hydroxygluterate | C03196 | 3.10 | 0.27 | Pyridoxine | C00314 | 0.86 | 1.14 |
Kynurenic acid | C01717 | 0.51 | 0.07 | L-Tryptophan | C00078 | 0.96 | 0.45 |
L-Glutamine | C00064 | 0.95 | 0.98 | 4-Pyridoxic acid | C00847 | 0.52 | 1.71 |
Pseudouridine | C02067 | 0.51 | 1.11 | Inositol | C00137 | 1.33 | 0.37 |
L-Lysine | C00047 | 0.67 | 0.97 | Uridine | C00299 | 0.94 | 0.88 |
Cytosine | C00380 | 0.57 | 0.79 | Ureidopropionic acid | C02642 | 0.76 | 0.15 |
5-Aminolevulinic acid | C00430 | 6.15 | 0.60 | Fumarate | C00122 | 0.96 | 0.47 |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
Submitted:
31 October 2023
Posted:
31 October 2023
You are already at the latest version
This version is not peer-reviewed
Submitted:
31 October 2023
Posted:
31 October 2023
You are already at the latest version
Medium | NaCl gradient (g·L-1) | NaNO3 gradient (g·L-1) | |
---|---|---|---|
Control | BBM | 0.025 | 0.25 |
High salinity | BBM | 5, 7.5, 10, 12.5 | 0.25 |
Low nitrogen | nitrogen-deficient BBM | 0.025 | 0, 0.032, 0.065, 0.13 |
Metabolite | KEGG code |
Fold change | Metabolite | KEGG code |
Fold change | ||
---|---|---|---|---|---|---|---|
HS vs CK | LN vs CK | HS vs CK | LN vs CK | ||||
N2,N2-Dimethylguanosine | NA | 0.35 | 0.33 | 6-Hydroxynicotinic acid | C01020 | 0.81 | 1.77 |
AMP | C00020 | 0.19 | 0.47 | N6-Acetyl-L-lysine | C02727 | 0.72 | 0.42 |
Glycerophosphocholine | C00670 | 0.73 | 0.57 | ATP | C00002 | 5.11 | 1.48 |
Glyceric acid | C00258 | 0.35 | 0.23 | L-Lactic acid | C01432 | 0.85 | 0.47 |
5-hydroxy-Tryptophan | C01017 | 0.15 | 0.46 | NAD | C00003 | 1.32 | 0.36 |
Nicotinic acid | C00253 | 0.43 | 0.48 | N-Acetyl-D-glucosamine | C00140 | 0.97 | 0.49 |
L-Aspartate | C00049 | 4.14 | 2.42 | NAAD | C00857 | 1.30 | 0.35 |
L-Proline | C00148 | 0.85 | 0.52 | N-Acetylcadaverine | NA | 1.85 | 0.69 |
Thymine | C00178 | 4.62 | 2.11 | dAMP | C00360 | 0.34 | 0.76 |
L-Carnitine | C00318 | 0.39 | 0.84 | Malate | C00711 | 0.92 | 0.34 |
UMP | C00105 | 0.31 | 0.41 | N-Carbamoyl-L-aspartic acid | C00438 | 1.99 | 0.63 |
cAMP | C00575 | 0.40 | 0.21 | Guanosine | C00387 | 1.75 | 0.38 |
ℽ-Glutamyl-L-methionine | NA | 3.09 | 1.17 | L-Asparagine | C00152 | 0.96 | 0.56 |
GDP | C00035 | 1.99 | 3.12 | Cytidine | C00475 | 0.72 | 0.75 |
Nicotinamide | C00153 | 1.80 | 1.53 | Arginine | C03406 | 0.57 | 0.25 |
Dimethylglycine | C01026 | 0.53 | 0.97 | Sucrose | C00089 | 1.17 | 0.53 |
2'-O-methyladenosine | C04779 | 0.71 | 0.35 | Orotic acid | C00295 | 0.26 | 0.67 |
ℽ -L-Glutamyl-L-phenylalanine | NA | 1.00 | 8.80 | Allantoic acid | C00499 | 0.31 | 0.50 |
5'-Deoxyadenosine | C05198 | 0.78 | 0.06 | L-Citrulline | C00327 | 2.35 | 0.52 |
5-Aminopentanoic acid | C00431 | 0.58 | 0.68 | Flavone | C15608 | 0.46 | 1.23 |
L-Tyrosine | C00082 | 4.51 | 0.80 | 7-methylguanosine | NA | 1.13 | 0.39 |
Pantothenic acid | C00864 | 0.88 | 0.44 | Riboflavin | C00255 | 0.72 | 1.12 |
L-Pipecolic acid | C00408 | 2.92 | 1.44 | FAD | C00016 | 1.24 | 0.45 |
Deoxycytidine | C00881 | 1.50 | 2.15 | cis-4-Hydroxy-D-proline | C03440 | 0.20 | 0.08 |
N-Acetylglutamine | NA | 1.97 | 1.42 | NADP | C00006 | 4.32 | 0.54 |
CMP | C00055 | 0.63 | 0.43 | Biopterin | C06313 | 0.36 | 1.29 |
Tryptamine | C00398 | 0.51 | 0.42 | L-Glutamate | C00025 | 1.05 | 0.40 |
Choline | C00114 | 0.50 | 1.03 | L-Homoserine | C00263 | 1.19 | 0.60 |
CDPcholine | C00307 | 0.49 | 0.38 | Hypoxanthine | C00262 | 0.46 | 1.30 |
Glycerol3P | C00093 | 0.37 | 0.38 | Pyridoxal | C00250 | 1.06 | 0.70 |
cis-Aconitate | C00417 | 1.97 | 2.78 | 2,3-Dihydroxybenzoic acid | C00196 | 1.34 | 0.25 |
Nicotinamide ribotide | C00455 | 3.47 | 3.62 | Cholesterol sulfate | C18043 | 1.39 | 1.56 |
Adenine | C00147 | 0.99 | 3.87 | N-Formylmethionine | C03145 | 1.62 | 0.18 |
N-Acetyl-L-alanine | NA | 0.38 | 0.31 | Glycyl-L-leucine | C02155 | 0.62 | 1.11 |
Xanthosine | C01762 | 0.51 | 0.36 | L-Valine | C00183 | 1.32 | 0.46 |
Deoxyguanosine | C00330 | 2.02 | 0.83 | 4-Guanidinobutyric acid | C01035 | 0.70 | 0.94 |
D-Neopterin | C05926 | 2.44 | 0.37 | FMN | C00061 | 1.60 | 0.94 |
Succinate | C00042 | 0.66 | 0.31 | Glutathione disulfide | C00127 | 1.85 | 0.66 |
O-Succinyl-L-homoserine | C01118 | 0.58 | 0.09 | Urocanic acid | C00785 | 0.59 | 0.59 |
Uric acid | C00366 | 1.18 | 1.41 | L-Methionine | C00073 | 1.39 | 0.23 |
N6-methyladenosine | NA | 0.75 | 0.24 | 2-keto-D-Gluconic acid | C06473 | 1.33 | 0.29 |
D-glucosamine 1-phosphate | C06156 | 0.48 | 0.32 | L-Homocysteic acid | C16511 | 1.18 | 0.64 |
Isobutyryl-CoA | C00630 | 7.57 | 0.92 | dTMP | C00364 | 0.56 | 1.20 |
DHAP | C00111 | 0.31 | 0.26 | Inosine | C00294 | 1.01 | 0.25 |
Thiamine | C00378 | 14.25 | 101.38 | L-Serine | C00065 | 1.23 | 0.40 |
GABA | C00334 | 1.84 | 1.16 | IMP | C00130 | 0.30 | 2.96 |
GDP-L-fucose | C00325 | 0.50 | 0.28 | L-2-Aminoadipic acid | C00956 | 1.13 | 0.78 |
Phenyllactic acid | C05607 | 3.24 | 0.62 | dGMP | C00362 | 0.42 | 2.51 |
D-Glucose-6-phosphate | C00092 | 0.77 | 0.42 | S-Adenosylhomocysteine | C00021 | 1.09 | 0.11 |
Glycine | C00037 | 2.16 | 0.41 | N4-Acetylcytidine | NA | 0.51 | 1.81 |
Creatine | C00300 | 1.26 | 1.12 | UDP-D-Glucuronate | C00167 | 2.13 | 0.27 |
1-Methylxanthine | C16358 | 0.61 | 0.16 | UDP -Glucose | C00029 | 1.70 | 0.90 |
Deoxyinosine | C05512 | 1.64 | 0.73 | L-Kynurenine | C00328 | 0.97 | 0.37 |
Dephospho-CoA | C00882 | 22.19 | 1.84 | N-Acetyl-L-phenylalanine | C03519 | 1.44 | 0.35 |
β-Hydroxybutyric acid | C01089 | 1.65 | 0.46 | L-Leucine | C00123 | 0.64 | 0.52 |
TPP | C00068 | 4.57 | 1.54 | L-Phenylalanine | C00079 | 0.95 | 0.65 |
ℽ -L-Glutamyl-L-valine | NA | 0.82 | 2.99 | taurine | C00245 | 1.13 | 0.24 |
Adenosine | C00212 | 1.13 | 0.33 | Acetyl-DL-Leucine | NA | 1.23 | 0.37 |
Phosphoenolpyruvate | C00074 | 0.77 | 0.35 | dCMP | C00239 | 0.44 | 1.32 |
L-2-Hydroxygluterate | C03196 | 3.10 | 0.27 | Pyridoxine | C00314 | 0.86 | 1.14 |
Kynurenic acid | C01717 | 0.51 | 0.07 | L-Tryptophan | C00078 | 0.96 | 0.45 |
L-Glutamine | C00064 | 0.95 | 0.98 | 4-Pyridoxic acid | C00847 | 0.52 | 1.71 |
Pseudouridine | C02067 | 0.51 | 1.11 | Inositol | C00137 | 1.33 | 0.37 |
L-Lysine | C00047 | 0.67 | 0.97 | Uridine | C00299 | 0.94 | 0.88 |
Cytosine | C00380 | 0.57 | 0.79 | Ureidopropionic acid | C02642 | 0.76 | 0.15 |
5-Aminolevulinic acid | C00430 | 6.15 | 0.60 | Fumarate | C00122 | 0.96 | 0.47 |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
Jinhu Wang
et al.
Water,
2022
© 2024 MDPI (Basel, Switzerland) unless otherwise stated