Review
Version 1
Preserved in Portico This version is not peer-reviewed
Nature-Derived Polysaccharide-Based Composite Hydrogels for Promoting Wound Healing
Version 1
: Received: 6 November 2023 / Approved: 7 November 2023 / Online: 7 November 2023 (11:14:38 CET)
A peer-reviewed article of this Preprint also exists.
Lee, H.; Jung, Y.; Lee, N.; Lee, I.; Lee, J.H. Nature-Derived Polysaccharide-Based Composite Hydrogels for Promoting Wound Healing. Int. J. Mol. Sci. 2023, 24, 16714. Lee, H.; Jung, Y.; Lee, N.; Lee, I.; Lee, J.H. Nature-Derived Polysaccharide-Based Composite Hydrogels for Promoting Wound Healing. Int. J. Mol. Sci. 2023, 24, 16714.
Abstract
Numerous innovative advancements in dressing technology for wound healing have emerged. Among the various types of wound dressings available, hydrogel dressings, structured with a three-dimensional network and composed of predominantly hydrophilic components, are widely used for wound care due to their remarkable capacity to absorb abundant wound exudate, maintain a moisture environment, provide soothing and cooling effects, and mimic the extracellular matrix. Composite hydrogel dressings, one of the evolved dressings, address the limitations of traditional hydrogel dressings by incorporating additional components, including particles, fibers, fabrics, or foams, within the hydrogels, effectively promoting wound treatment and healing. The added elements enhance the features or add specific functionalities of the dressings, such as sensitivity to external factors, adhesiveness, mechanical strength, control over the release of therapeutic agents, antioxidant and antimicrobial properties, and tissue regeneration behavior. They can be categorized as natural or synthetic based on the origin of the main components of the hydrogel network. This review focuses on recent research on developing natural polysaccharide-based composite hydrogel wound dressings. Their preparation and composition, the reinforcement materials integrated into hydrogels, and therapeutic agents are also explored. Furthermore, their features and the specific types of wounds where applied are discussed as well.
Keywords
natural polysaccharide; composite hydrogel; wound healing; therapeutic agent
Subject
Chemistry and Materials Science, Polymers and Plastics
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Comments (0)
We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.
Leave a public commentSend a private comment to the author(s)
* All users must log in before leaving a comment