Version 1
: Received: 16 November 2023 / Approved: 16 November 2023 / Online: 17 November 2023 (08:43:27 CET)
Version 2
: Received: 8 July 2024 / Approved: 9 July 2024 / Online: 9 July 2024 (10:47:28 CEST)
How to cite:
Muñoz, F.; Haidar, Z. S.; Puigdollers, A.; Guerra, I.; Padilla, M. C.; Ortega, N.; Balcells, M.; García, M. J. Efficient Hydroxyapatite Extraction From Salmon Bone Waste: An Improved Lab-Scaled Physico-Chemico-Biological Process. Preprints2023, 2023111090. https://doi.org/10.20944/preprints202311.1090.v2
Muñoz, F.; Haidar, Z. S.; Puigdollers, A.; Guerra, I.; Padilla, M. C.; Ortega, N.; Balcells, M.; García, M. J. Efficient Hydroxyapatite Extraction From Salmon Bone Waste: An Improved Lab-Scaled Physico-Chemico-Biological Process. Preprints 2023, 2023111090. https://doi.org/10.20944/preprints202311.1090.v2
Muñoz, F.; Haidar, Z. S.; Puigdollers, A.; Guerra, I.; Padilla, M. C.; Ortega, N.; Balcells, M.; García, M. J. Efficient Hydroxyapatite Extraction From Salmon Bone Waste: An Improved Lab-Scaled Physico-Chemico-Biological Process. Preprints2023, 2023111090. https://doi.org/10.20944/preprints202311.1090.v2
APA Style
Muñoz, F., Haidar, Z. S., Puigdollers, A., Guerra, I., Padilla, M. C., Ortega, N., Balcells, M., & García, M. J. (2024). Efficient Hydroxyapatite Extraction From Salmon Bone Waste: An Improved Lab-Scaled Physico-Chemico-Biological Process. Preprints. https://doi.org/10.20944/preprints202311.1090.v2
Chicago/Turabian Style
Muñoz, F., Mercedes Balcells and María José García. 2024 "Efficient Hydroxyapatite Extraction From Salmon Bone Waste: An Improved Lab-Scaled Physico-Chemico-Biological Process" Preprints. https://doi.org/10.20944/preprints202311.1090.v2
Abstract
Salmon aquaculture generates a substantial volume of waste material, offering potential for biomaterial production. This industry produces significant waste, which can be repurposed for various biological applications, particularly in biomaterial production for tissue engineering with pertinent applications in osteo-conduction, osteo-induction, and clinical/surgical bone regeneration and repair. The process involves a standardized pre-treatment stage aimed at minimizing biological waste content. Subsequently, the treatment stage, contingent on the chosen methodology, facilitates the removal of proteins, lipids, molecules, and other compounds, leaving the mineral phase as a valuable substrate. The selection of the optimal method, whether alkaline hydrolysis, calcination, or NaOH hydrolysis, for obtaining this substrate necessitates thorough examination through chemical, physical, and biological assessments, including Raman Spectroscopy and X-Ray Diffraction. This study aims to identify the most efficient laboratory process for biofunctional nano-sized hydroxyapatite mineral production derived from Chilean salmon fish backbone waste.
Keywords
Hydroxyapatite; Salmon Bone; Bone Repair; Biomaterial; Osteoregeneration; Process
Subject
Engineering, Bioengineering
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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