Ferrari, I.V. Novel Perspectives on Amentoflavone’s Influence on Cell Cycle and Apoptosis: Exploring Theoretical Modulation of Serine/Threonine-Kinases. African Research Journal of Medical Sciences 2024, 1, 14–19, doi:10.62587/afrjms.1.2.2024.14-19.
Ferrari, I.V. Novel Perspectives on Amentoflavone’s Influence on Cell Cycle and Apoptosis: Exploring Theoretical Modulation of Serine/Threonine-Kinases. African Research Journal of Medical Sciences 2024, 1, 14–19, doi:10.62587/afrjms.1.2.2024.14-19.
Ferrari, I.V. Novel Perspectives on Amentoflavone’s Influence on Cell Cycle and Apoptosis: Exploring Theoretical Modulation of Serine/Threonine-Kinases. African Research Journal of Medical Sciences 2024, 1, 14–19, doi:10.62587/afrjms.1.2.2024.14-19.
Ferrari, I.V. Novel Perspectives on Amentoflavone’s Influence on Cell Cycle and Apoptosis: Exploring Theoretical Modulation of Serine/Threonine-Kinases. African Research Journal of Medical Sciences 2024, 1, 14–19, doi:10.62587/afrjms.1.2.2024.14-19.
Abstract
Docking results suggest that Amentoflavone has a higher affinity for investigated Serine/threonine-protein kinases, indicating potential interactions that may influence the activities of these kinases. The negative values of the binding energies signify strong and stable interactions, suggesting that Amentoflavone could be a key molecule in modulating the functions of these kinases, which play crucial roles in cellular processes such as cell cycle regulation and apoptosis.
Keywords
serine/threonine protein kinase; amentoflavone; molecular docking; apoptosis
Subject
Medicine and Pharmacology, Medicine and Pharmacology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.