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Cognitive Impairment and Brain Atrophy in Patients with Non-Dialysis and Dialysis Dependent Chronic Kidney Disease
Version 1
: Received: 17 January 2024 / Approved: 18 January 2024 / Online: 18 January 2024 (15:58:37 CET)
A peer-reviewed article of this Preprint also exists.
Tsuruya, K.; Yoshida, H. Cognitive Impairment and Brain Atrophy in Patients with Chronic Kidney Disease. J. Clin. Med. 2024, 13, 1401. Tsuruya, K.; Yoshida, H. Cognitive Impairment and Brain Atrophy in Patients with Chronic Kidney Disease. J. Clin. Med. 2024, 13, 1401.
Abstract
In our country, the aging society is rapidly progressing, with an increase in patients with chronic kidney disease (CKD) and those undergoing dialysis, coupled with the aging of the population. As a result, the number of individuals with cognitive impairment (CI) is rising, and addressing this issue has become an urgent problem. One characteristic of dementia in CKD patients is the high frequency of vascular dementia, making the prevention through the management of classical risk factors such as hypertension, diabetes mellitus, dyslipidemia, smoking, etc., associated with atherosclerosis and arteriosclerosis. Other effective measures, including the use of renin-angiotensin system inhibitors, addressing anemia, exercise therapy, and lifestyle improvements, have been reported. Incidence and progression of CI may also be influenced by the type of dialysis or kidney replacement therapy, with reports suggesting that long-duration dialysis, low-temperature hemodialysis, peritoneal dialysis, and kidney transplantation (KTx) can have a possible preferable effect on preserving cognitive function.
Keywords
brain atrophy; cognitive impairment; chronic kidney disease; dialysis; exercise
Subject
Medicine and Pharmacology, Urology and Nephrology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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