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Systemic Inflammation Index: A New Candidate Minor Criterion in the Diagnosis of Polycythemia vera
Version 1
: Received: 7 March 2024 / Approved: 7 March 2024 / Online: 7 March 2024 (12:04:07 CET)
A peer-reviewed article of this Preprint also exists.
Gulturk, E.; Kapucu, K. The Systemic Inflammation Index: A New Candidate Minor Criterion in the Diagnosis of Polycythemia Vera. J. Pers. Med. 2024, 14, 471. Gulturk, E.; Kapucu, K. The Systemic Inflammation Index: A New Candidate Minor Criterion in the Diagnosis of Polycythemia Vera. J. Pers. Med. 2024, 14, 471.
Abstract
Aim: To investigate inflammation indices and erythropoietin (EPO) levels for their potential role in distinguishing polycythemia vera (PV) from secondary polycythemia (SP), and to compare different parameter combinations in terms of diagnostic accuracy. Methods: This retrospective cohort was created from patients assessed for polycythemia from January 2020 to December 2023. PV diagnosis was made according to the 2016 WHO criteria (n=145). Those who did not fulfill the criteria were defined as having SP (n=84). Results: NLR, PLR and SII were significantly higher in the PV group (p
Keywords
polycythemia vera; secondary polycythemia; systemic inflammation index; erythropoietin; neutrophil-to-lymphocyte ratio; platelet-to-lymphocyte ratio
Subject
Medicine and Pharmacology, Hematology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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