PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
Antimicrobial and Antifungal Action of Biogenic Silver Nanoparticles in Combination with Antibiotics and Fungicides, against Opportunistic Bacteria and Yeast
Version 1
: Received: 1 May 2024 / Approved: 2 May 2024 / Online: 2 May 2024 (09:46:40 CEST)
How to cite:
Rozhin, A.; Batasheva, S.; Iskuzhina, L.; Gomzikova, M.; Kryuchkova, M. Antimicrobial and Antifungal Action of Biogenic Silver Nanoparticles in Combination with Antibiotics and Fungicides, against Opportunistic Bacteria and Yeast. Preprints2024, 2024050109. https://doi.org/10.20944/preprints202405.0109.v1
Rozhin, A.; Batasheva, S.; Iskuzhina, L.; Gomzikova, M.; Kryuchkova, M. Antimicrobial and Antifungal Action of Biogenic Silver Nanoparticles in Combination with Antibiotics and Fungicides, against Opportunistic Bacteria and Yeast. Preprints 2024, 2024050109. https://doi.org/10.20944/preprints202405.0109.v1
Rozhin, A.; Batasheva, S.; Iskuzhina, L.; Gomzikova, M.; Kryuchkova, M. Antimicrobial and Antifungal Action of Biogenic Silver Nanoparticles in Combination with Antibiotics and Fungicides, against Opportunistic Bacteria and Yeast. Preprints2024, 2024050109. https://doi.org/10.20944/preprints202405.0109.v1
APA Style
Rozhin, A., Batasheva, S., Iskuzhina, L., Gomzikova, M., & Kryuchkova, M. (2024). Antimicrobial and Antifungal Action of Biogenic Silver Nanoparticles in Combination with Antibiotics and Fungicides, against Opportunistic Bacteria and Yeast. Preprints. https://doi.org/10.20944/preprints202405.0109.v1
Chicago/Turabian Style
Rozhin, A., Marina Gomzikova and Marina Kryuchkova. 2024 "Antimicrobial and Antifungal Action of Biogenic Silver Nanoparticles in Combination with Antibiotics and Fungicides, against Opportunistic Bacteria and Yeast" Preprints. https://doi.org/10.20944/preprints202405.0109.v1
Abstract
The development of multidrug resistance by pathogenic bacteria and yeast is a significant medical problem that needs to be addressed. One possible answer could be the combined use of antibiotics and silver nanoparticles, which have different mechanisms of antimicrobial action. Nanoparticles can be combined with antifungal agents in the same way. Biogenic silver nanoparticles synthesized using environmentally friendly technology using extracts of biologically active plants are an effective nanomaterial that needs to be comprehensively investigated for implementation into medical practice. In this study, the synergistic effects arising from their combined use with antibiotics and fungicides against various bacteria and yeasts, included in the ESKAPE list, were studied. Effective concentrations of substances were established, recommendations for the studied pathogenic species were presented and the effect of destruction of the bacterial membrane was illustrated. The most significant synergistic effect was manifested in pathogenic candida and brewer's yeast.
Medicine and Pharmacology, Epidemiology and Infectious Diseases
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.