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Exploring the Phytochemical Composition and the Bioactive Properties of Malbec and Torrontés Wine Pomace from the Calchaquíes Valleys (Argentina) for their Sustainable Exploitation
Tapia, P.E.; Silva, A.M.; Delerue-Matos, C.; Moreira, M.; Rodrigues, F.; Torres Carro, R.; Santi, M.D.; Ortega, M.G.; Blázquez, M.A.; Arena, M.E.; Alberto, M.R. Exploring the Phytochemical Composition and the Bioactive Properties of Malbec and Torrontés Wine Pomaces from the Calchaquíes Valleys (Argentina) for Their Sustainable Exploitation. Foods2024, 13, 1795.
Tapia, P.E.; Silva, A.M.; Delerue-Matos, C.; Moreira, M.; Rodrigues, F.; Torres Carro, R.; Santi, M.D.; Ortega, M.G.; Blázquez, M.A.; Arena, M.E.; Alberto, M.R. Exploring the Phytochemical Composition and the Bioactive Properties of Malbec and Torrontés Wine Pomaces from the Calchaquíes Valleys (Argentina) for Their Sustainable Exploitation. Foods 2024, 13, 1795.
Tapia, P.E.; Silva, A.M.; Delerue-Matos, C.; Moreira, M.; Rodrigues, F.; Torres Carro, R.; Santi, M.D.; Ortega, M.G.; Blázquez, M.A.; Arena, M.E.; Alberto, M.R. Exploring the Phytochemical Composition and the Bioactive Properties of Malbec and Torrontés Wine Pomaces from the Calchaquíes Valleys (Argentina) for Their Sustainable Exploitation. Foods2024, 13, 1795.
Tapia, P.E.; Silva, A.M.; Delerue-Matos, C.; Moreira, M.; Rodrigues, F.; Torres Carro, R.; Santi, M.D.; Ortega, M.G.; Blázquez, M.A.; Arena, M.E.; Alberto, M.R. Exploring the Phytochemical Composition and the Bioactive Properties of Malbec and Torrontés Wine Pomaces from the Calchaquíes Valleys (Argentina) for Their Sustainable Exploitation. Foods 2024, 13, 1795.
Abstract
Hydroalcoholic extracts from Malbec and Torrontés wine pomace (Vitis vinifera L.) originating from the high-altitude vineyards of Argentina's Calchaquí Valleys were characterized. Total phenolics, hydroxycinnamic acids, orthodiphenols, anthocyanins, non-flavonoid phenolics, total flavonoids, flavones/flavonols, flavanones/dihydroflavonols, and tannins were quanti-fied through spectrophotometric methods, with Malbec extract exhibiting higher concentra-tions in most of phytochemical groups when compared to Torrontés. HPLC-DAD identified more than 30 phenolic compounds in both extracts. Malbec displayed superior antiradical ac-tivity (ABTS cation, nitric oxide, and superoxide anion radicals), reduction power (iron, copper and phosphomolybdenum), hypochlorite scavenging, and iron chelating ability, compara-tively to Torrontés. The cytotoxicity assessments revealed that Torrontés affected the viability of HT29-MTX and Caco-2 colon cancer cells by 70% and 50%, respectively, at the highest tested concentration (1 mg/mL). At the same time, both extracts did not demonstrate acute toxicity in Artemia salina or in red blood cell assays at 500 µg/mL. Both extracts inhibited the lipoxygen-ase enzyme, with Malbec also reducing the tyrosinase activity and neither inhibited the xan-thine oxidase. The substantial phenolic content and diverse biological activities in Calchaquí Valleys' pomaces underline their potentialities to be valorized for pharmaceutical, cosmetic, and food industries.
Keywords
Vitis vinifera; antioxidant; cancer cell cytotoxicity; tyrosinase; lipoxygenase; xanthine oxidase
Subject
Biology and Life Sciences, Food Science and Technology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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