Version 1
: Received: 6 June 2024 / Approved: 7 June 2024 / Online: 7 June 2024 (08:00:21 CEST)
How to cite:
Saied Sabir, M. I.; Alrasheid, A. A. Comparative Study of Phytochemical Analysis and Anti-Microbial Activity of Ziziphus spina-christi L. Leaves Extracts From Different Areas in Sudan. Preprints2024, 2024060466. https://doi.org/10.20944/preprints202406.0466.v1
Saied Sabir, M. I.; Alrasheid, A. A. Comparative Study of Phytochemical Analysis and Anti-Microbial Activity of Ziziphus spina-christi L. Leaves Extracts From Different Areas in Sudan. Preprints 2024, 2024060466. https://doi.org/10.20944/preprints202406.0466.v1
Saied Sabir, M. I.; Alrasheid, A. A. Comparative Study of Phytochemical Analysis and Anti-Microbial Activity of Ziziphus spina-christi L. Leaves Extracts From Different Areas in Sudan. Preprints2024, 2024060466. https://doi.org/10.20944/preprints202406.0466.v1
APA Style
Saied Sabir, M. I., & Alrasheid, A. A. (2024). Comparative Study of Phytochemical Analysis and Anti-Microbial Activity of <em>Ziziphus spina-christi</em> L. Leaves Extracts From Different Areas in Sudan. Preprints. https://doi.org/10.20944/preprints202406.0466.v1
Chicago/Turabian Style
Saied Sabir, M. I. and Ayat Ahmed Alrasheid. 2024 "Comparative Study of Phytochemical Analysis and Anti-Microbial Activity of <em>Ziziphus spina-christi</em> L. Leaves Extracts From Different Areas in Sudan" Preprints. https://doi.org/10.20944/preprints202406.0466.v1
Abstract
We conducted a study exploring the potential of the medicinal plant Ziziphus spina-christi as a source of antimicrobial compounds. With the growing threat of antibiotic resistance, we were particularly interested in evaluating plant-derived natural products for their ability to fight infections. We collected Z. spina-christi leaves from four different regions in Sudan and extracted them with ethanol. Our phytochemical screening revealed the presence of several secondary metabolites, including flavonoids, triterpenes, sterols, tannins, saponins, cardiac glycosides, and reducing sugars. Alkaloids and anthraquinones were not detected. We then tested the ethanolic extracts for antimicrobial activity against a range of bacterial and fungal pathogens using the agar well diffusion method. Interestingly, we observed significant differences between the extracts from different locations. The extract from Khartoum city exhibited the highest antimicrobial potency, followed by the extracts from Al-Rahad, Al-Hidiba, and finally Al Damazin. Based on these findings, we concluded that Z. spina-christi leaves contain a diverse array of phytochemicals with potential medicinal applications. The variation in antimicrobial effects between the extracts may be attributed to environmental factors influencing the plant's chemical composition. Further research is warranted to identify the specific bioactive compounds responsible for the observed antimicrobial activities. This could pave the way for the development of plant-based antimicrobial agents to combat drug-resistant pathogens and alleviate the global public health crisis posed by the rise of antibiotic resistance.
Keywords
Ziziphus spina-christi; medicinal plants; phytochemical analysis; leaves extracts; zone of inhibition
Subject
Biology and Life Sciences, Biology and Biotechnology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
