Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Exploring the Relationship Between Inhaled Corticosteroid Usage, Asthma Severity, and Sleep-Disordered Breathing: A Systematic Literature Review

Version 1 : Received: 12 June 2024 / Approved: 12 June 2024 / Online: 13 June 2024 (11:51:30 CEST)

How to cite: Zaffanello, M.; Ferrante, G.; Piazza, M.; Nosetti, L.; Tenero, L.; Piacentini, G. Exploring the Relationship Between Inhaled Corticosteroid Usage, Asthma Severity, and Sleep-Disordered Breathing: A Systematic Literature Review. Preprints 2024, 2024060873. https://doi.org/10.20944/preprints202406.0873.v1 Zaffanello, M.; Ferrante, G.; Piazza, M.; Nosetti, L.; Tenero, L.; Piacentini, G. Exploring the Relationship Between Inhaled Corticosteroid Usage, Asthma Severity, and Sleep-Disordered Breathing: A Systematic Literature Review. Preprints 2024, 2024060873. https://doi.org/10.20944/preprints202406.0873.v1

Abstract

Additionally, the characteristics of inhaled corticosteroids (inhaled particle sizes) may influence the risk of sleep apnea. In children, the severity of asthma plays a crucial role in influencing the prevalence of sleep apnea, while using inhaled corticosteroids seems to be a less relevant risk factor compared to adults. The overall risk of bias was categorized as high or with some concerns in 100% of the studies analyzed. Each study identified at least one form of bias that raised significant concerns. Studies showed a complex relationship between inhaled corticosteroids use, asthma severity, and the onset of sleep apnea. Further studies are needed.

Keywords

asthma; fluticasone propionate; inhaled corticosteroid; obstructive sleep apnea; sleep-disordered breathing

Subject

Public Health and Healthcare, Primary Health Care

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