Preprint Case Report Version 2 This version is not peer-reviewed

Gallbladder Burkitt’s Lymphoma: A Literature Review Including a Case Report in a Child Living with HIV

Version 1 : Received: 16 June 2024 / Approved: 17 June 2024 / Online: 17 June 2024 (08:06:08 CEST)
Version 2 : Received: 9 September 2024 / Approved: 9 September 2024 / Online: 10 September 2024 (10:43:52 CEST)

How to cite: Duarte, N. L.; Bueno, A. P. S.; Sanches, B. S.; Ramos, G. A.; Batista, L. A.; Abreu, T. F. D.; Land, M. G. P.; Milito, C. B. Gallbladder Burkitt’s Lymphoma: A Literature Review Including a Case Report in a Child Living with HIV. Preprints 2024, 2024061084. https://doi.org/10.20944/preprints202406.1084.v2 Duarte, N. L.; Bueno, A. P. S.; Sanches, B. S.; Ramos, G. A.; Batista, L. A.; Abreu, T. F. D.; Land, M. G. P.; Milito, C. B. Gallbladder Burkitt’s Lymphoma: A Literature Review Including a Case Report in a Child Living with HIV. Preprints 2024, 2024061084. https://doi.org/10.20944/preprints202406.1084.v2

Abstract

Malignant lymphoma is an unusual form of gallbladder neoplasm. Almost all of these tumors are diffuse large B-cell lymphomas or mucosa-associated lymphoid tissue-type lymphomas. Herein, we report a rare case of a gallbladder Burkitt’s lymphoma (BL) in a child living with HIV. As far as we are concerned, this is the secondfirst report in the pediatric population and the first one in an individual living with HIV. The patient (a five-year-old black female child) attended the Federal Hospital of Lagoa, Rio de Janeiro, Brazil, underwent cholecystectomy and the postoperative pathological analysis of the gallbladder revealed a diagnosis of BL (EBV-positive). Also, HIV serology was performed and returned positive. She was transferred to the Martagão Gesteira Institute of Pediatrics and Childcare for oncological treatment, dying from sepsis and disease progression about 18 months later. Patient did not undergo ART/cART. Previous cases of gallbladder BL were herein described and analyzed to characterize the clinicopathological features and possible similarities. BL can occur in the gallbladder both in the context of HIV infection and in the pediatric population. Biopsy is mandatory in cases with suggestive findings of lymphoma, and an early diagnosis can change the course of the disease. Furthermore, the case highlights the importance of an early initiation of ART/cART in people living with HIV (PLWH).

Keywords

Burkitt’s lymphoma; gallbladder; malignant lymphoma; gallbladder cancer; HIV; pediatric; case report; Brazil

Subject

Medicine and Pharmacology, Hematology

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.