Pérez-Medina, T.; Garcia-Benasach, F.; Royuela, A.; Gomez-Manrique, A.; García-Cardoso, M.; Chaves, P.; Pereira, A. COVID-19 Disease during Pregnancy. Gestational Duration and Fetal Weight: Two Understudied Adverse Outcomes. Preprints2024, 2024061612. https://doi.org/10.20944/preprints202406.1612.v1
APA Style
Pérez-Medina, T., Garcia-Benasach, F., Royuela, A., Gomez-Manrique, A., García-Cardoso, M., Chaves, P., & Pereira, A. (2024). COVID-19 Disease during Pregnancy. Gestational Duration and Fetal Weight: Two Understudied Adverse Outcomes. Preprints. https://doi.org/10.20944/preprints202406.1612.v1
Chicago/Turabian Style
Pérez-Medina, T., Pilar Chaves and Augusto Pereira. 2024 "COVID-19 Disease during Pregnancy. Gestational Duration and Fetal Weight: Two Understudied Adverse Outcomes" Preprints. https://doi.org/10.20944/preprints202406.1612.v1
Abstract
Abstract: (1) Background: to find out how COVID-19 infection during pregnancy affects the outcome of the pregnancy; (2) Methods: 166 SARS-CoV-2-positive pregnant women formed the study group. 128 SARS-CoV-2-negative pregnant women formed the control group. Anatomopathological study of the placenta was performed in all cases; (3) Results: Placental insufficiency appeared in 38 patients (22.9%) of the study group and in 17 patients (13.2%) in the control group (p=0.016). Villitis appeared in 50 patients (30.1%) of the study group and in 16 (12.6%) in the control group (p=0.000). 166 COVID-19 positive patients were further subdivided, into those with anatomopathological affection of the placenta, and those without. When gestational age between patients with placental insufficiency and those without it are compared, a difference of 4.38 days is obtained (p=0.0393). If we compare neonatal weight between patients with placental insufficiency and those without it, a difference of 406.4 grams is obtained (p=0.0000). When gestational age between patients with villitis and those with-out it are compared, a difference of 3.2 days is found (p=0.0919). When neonatal weight between patients with villitis and those without it are compared, a difference of 242.2 grams is obtained (p=0.0018). (4) Conclusions: COVID-19 infection during pregnancy may produce lower fetal weight and shorter gestational length.
Medicine and Pharmacology, Obstetrics and Gynaecology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
,
,
