Version 1
: Received: 28 June 2024 / Approved: 28 June 2024 / Online: 1 July 2024 (09:14:34 CEST)
How to cite:
Ruíz-Baltazar, Á. D. J.; Reyes-López, S. Y.; Méndez-Lozano, N.; Juarez-Moreno, K. Evaluation of Superparamagnetic Fe3O4-Ag Decorated Nanoparticles: Cytotoxicity Studies in Human Fibroblasts (HFF-1) and Breast Cancer Cells (MCF-7). Preprints2024, 2024070009. https://doi.org/10.20944/preprints202407.0009.v1
Ruíz-Baltazar, Á. D. J.; Reyes-López, S. Y.; Méndez-Lozano, N.; Juarez-Moreno, K. Evaluation of Superparamagnetic Fe3O4-Ag Decorated Nanoparticles: Cytotoxicity Studies in Human Fibroblasts (HFF-1) and Breast Cancer Cells (MCF-7). Preprints 2024, 2024070009. https://doi.org/10.20944/preprints202407.0009.v1
Ruíz-Baltazar, Á. D. J.; Reyes-López, S. Y.; Méndez-Lozano, N.; Juarez-Moreno, K. Evaluation of Superparamagnetic Fe3O4-Ag Decorated Nanoparticles: Cytotoxicity Studies in Human Fibroblasts (HFF-1) and Breast Cancer Cells (MCF-7). Preprints2024, 2024070009. https://doi.org/10.20944/preprints202407.0009.v1
APA Style
Ruíz-Baltazar, Á. D. J., Reyes-López, S. Y., Méndez-Lozano, N., & Juarez-Moreno, K. (2024). Evaluation of Superparamagnetic Fe3O4-Ag Decorated Nanoparticles: Cytotoxicity Studies in Human Fibroblasts (HFF-1) and Breast Cancer Cells (MCF-7). Preprints. https://doi.org/10.20944/preprints202407.0009.v1
Chicago/Turabian Style
Ruíz-Baltazar, Á. D. J., Néstor Méndez-Lozano and Karla Juarez-Moreno. 2024 "Evaluation of Superparamagnetic Fe3O4-Ag Decorated Nanoparticles: Cytotoxicity Studies in Human Fibroblasts (HFF-1) and Breast Cancer Cells (MCF-7)" Preprints. https://doi.org/10.20944/preprints202407.0009.v1
Abstract
This study investigates the cytotoxicity profile of superparamagnetic Fe3O4-Ag decorated nanoparticles against human fibroblasts (HFF-1) and breast cancer cells (MCF-7). The nanoparticles underwent comprehensive characterization employing scanning electron microscopy (SEM), X-ray diffraction (XRD) analysis, X-ray photoelectron spectroscopy (XPS), and magnetic assays including hysteresis curves and zero-field-cooled (ZFC) plots. Notably, the nanoparticles exhibited superparamagnetic behavior as evidenced by magnetic studies. Remarkably, cytotoxicity assays demonstrated that both HFF-1 and MCF-7 cells maintained nearly 100% viability upon nanoparticle exposure. These results underscore the outstanding biocompatibility of Fe3O4/Ag decorated nanoparticles, suggesting their potential utility in biomedical applications such as drug delivery and magnetic targeting without inducing significant cytotoxic effects. This investigation advances our understanding of the behavior of nanostructured materials in biological settings and highlights their promising prospects in biomedicine.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
