Communication
Version 1
This version is not peer-reviewed
Celiac Disease Image Classification using Convolutional Neural Network
Version 1
: Received: 3 July 2024 / Approved: 3 July 2024 / Online: 3 July 2024 (10:11:00 CEST)
How to cite: Carreras, J. Celiac Disease Image Classification using Convolutional Neural Network. Preprints 2024, 2024070329. https://doi.org/10.20944/preprints202407.0329.v1 Carreras, J. Celiac Disease Image Classification using Convolutional Neural Network. Preprints 2024, 2024070329. https://doi.org/10.20944/preprints202407.0329.v1
Abstract
Celiac disease is a gluten-sensitive immune-mediated enteropathy of the small intestine that occurs in genetically predisposed individuals. Abnormal immune response results in mucosal inflammation, villous atrophy, and crypt hyperplasia. This study was a proof-of-concept exercise that used a convolutional neural network to classify hematoxylin and eosin (H&E) histological images of celiac disease, normal small intestine control, and non-specified duodenal inflammation; 7294, 11,642, and 5966 images, respectively. The trained network classified celiac disease images with high performance (accuracy 99.7%, precision 99.6%, recall 99.3%, F1-score 99.5%, and specificity 99.8%). Interestingly, when the same network (already trained for the 3 class images), analyzed duodenal adenocarcinoma (3723 images), the new images were classified as duodenal inflammation in 63.65%, small intestine control in 34.73%, and celiac disease in 1.61% of the cases. Finally, when the network was retrained using the 4 histological subtypes of images, all performance parameters were above 99% for celiac disease. In conclusion, the convolutional neural network (CNN)-based deep neural system was able to classify medical histological images with high performance. Narrow artificial intelligence (AI) is designed to perform tasks that typically require human intelligence, but it operates within limited constraints and is task specific.
Keywords
artificial intelligence; convolutional neural network; computer vision; transfer learning; inflammatory bowel disease; celiac disease; machine learning; duodenum; inflammation; neoplasia; carcinoma
Subject
Medicine and Pharmacology, Pathology and Pathobiology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Comments (0)
We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.
Leave a public commentSend a private comment to the author(s)
* All users must log in before leaving a comment