Preprint Article Version 1 This version is not peer-reviewed

Evidence On Viral Suppression Supports Scaling-Up Transition To Dolutegravir-Based Regimens In Pediatric Populations In Cameroon: A Multicentre Baseline Assessment For The Cipher-Adola Study

Version 1 : Received: 4 July 2024 / Approved: 5 July 2024 / Online: 5 July 2024 (12:31:56 CEST)

How to cite: FOKAM, J.; Bouba, Y.; Ajeh, R. A.; Guebiapsi, D. T.; Essamba, S.; Zeh Meka, A. F.; Lifanda, E.; Ada, R. A.; Liman, Y.; Mbengono, N. B.; Djomo, A. R. D.; Tetang, S. N.; Sosso, S. M.; Babodo, J. C.; Ambomo, O. F. N.; Temgoua, E. M.; Medouane, C.; Atsinkou, S. N.; Mvogo, J. L.; Onana, R. M.; Anoubissi, J. D. D.; Ketchaji, A.; Nka, A. D.; Gouissi, D.-H. A.; Ka’e, A. C.; Fainguem, N. N.; Kamgaing, R. S.; Takou, D. A. K.; Tchouaket, M. C. T.; Semengue, E. N. J.; Amougou, M. A.; Nwobegahay, J.; Vuchas, C.; Nsimen, A. N.; Eyoum, B. B.; Gatchuessi, S. K.; Ateba, F. N.; Kesseng, D.; Billong, S. C.; Armenia, D.; Santoro, M. M.; Ceccherini-Silberstein, F.; Koki, P. N.; Hamsatou, H. C.; Colizzi, V.; Ndjolo, A.; Perno, C. F.; Zoung-Kanyi Bissek, A.-C. Evidence On Viral Suppression Supports Scaling-Up Transition To Dolutegravir-Based Regimens In Pediatric Populations In Cameroon: A Multicentre Baseline Assessment For The Cipher-Adola Study. Preprints 2024, 2024070512. https://doi.org/10.20944/preprints202407.0512.v1 FOKAM, J.; Bouba, Y.; Ajeh, R. A.; Guebiapsi, D. T.; Essamba, S.; Zeh Meka, A. F.; Lifanda, E.; Ada, R. A.; Liman, Y.; Mbengono, N. B.; Djomo, A. R. D.; Tetang, S. N.; Sosso, S. M.; Babodo, J. C.; Ambomo, O. F. N.; Temgoua, E. M.; Medouane, C.; Atsinkou, S. N.; Mvogo, J. L.; Onana, R. M.; Anoubissi, J. D. D.; Ketchaji, A.; Nka, A. D.; Gouissi, D.-H. A.; Ka’e, A. C.; Fainguem, N. N.; Kamgaing, R. S.; Takou, D. A. K.; Tchouaket, M. C. T.; Semengue, E. N. J.; Amougou, M. A.; Nwobegahay, J.; Vuchas, C.; Nsimen, A. N.; Eyoum, B. B.; Gatchuessi, S. K.; Ateba, F. N.; Kesseng, D.; Billong, S. C.; Armenia, D.; Santoro, M. M.; Ceccherini-Silberstein, F.; Koki, P. N.; Hamsatou, H. C.; Colizzi, V.; Ndjolo, A.; Perno, C. F.; Zoung-Kanyi Bissek, A.-C. Evidence On Viral Suppression Supports Scaling-Up Transition To Dolutegravir-Based Regimens In Pediatric Populations In Cameroon: A Multicentre Baseline Assessment For The Cipher-Adola Study. Preprints 2024, 2024070512. https://doi.org/10.20944/preprints202407.0512.v1

Abstract

Mortality in children accounts for 15% of all AIDS-related deaths globally, with a higher burden among Cameroonian children (25%), likely due to poor virological response. We sought to evaluate viral suppression (VS) and its determinants in a nationally representative paediatric and young adult population receiving antiretroviral therapy (ART). A cross-sectional and multicentric study was conducted among Cameroonian children (

Keywords

Virological suppression; low level viremia; children, adolescents, and young-adults; DTG-based regimen; elimination of paediatric AIDS; Cameroon.

Subject

Medicine and Pharmacology, Medicine and Pharmacology

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