Preprint Article Version 1 This version is not peer-reviewed

Radish Root Ferment Filtrate for Cosmetic Preservation: A Study of Efficacy of Kopraphinol©

Version 1 : Received: 11 July 2024 / Approved: 11 July 2024 / Online: 11 July 2024 (16:37:44 CEST)

How to cite: Juliano, C. C.; Magrini, G. A. Radish Root Ferment Filtrate for Cosmetic Preservation: A Study of Efficacy of Kopraphinol©. Preprints 2024, 2024070976. https://doi.org/10.20944/preprints202407.0976.v1 Juliano, C. C.; Magrini, G. A. Radish Root Ferment Filtrate for Cosmetic Preservation: A Study of Efficacy of Kopraphinol©. Preprints 2024, 2024070976. https://doi.org/10.20944/preprints202407.0976.v1

Abstract

The objective of this investigation was to characterize the antimicrobial activity of the natural preservative, intended for cosmetic purpose, Kopraphinol (INCI name: Lactobacillus/Radish Root Ferment Extract Filtrate). It was tested against a panel of selected bacteria and mycetes by using conventional microbiological techniques (determination of MIC, time killing assay), and a chal-lenge test was used to verify its potential preservative in an O/W cream. Kopraphinol has shown an interesting antimicrobial effectiveness comparable to methylparaben. Moreover, it fulfilled challenge test criterion A and has proven effective against microbial contamination. The results obtained show that Kopraphinol can be considered a promising and effective candidate for anti-microbial preservation of cosmetics and could successfully complement or even replace conven-tional preservatives.

Keywords

cosmetic preservatives; Lactobacillus/Radish Root Ferment Extract Filtrate; Kopraphinol©; Challenge test; MIC

Subject

Chemistry and Materials Science, Applied Chemistry

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