Version 1
: Received: 15 July 2024 / Approved: 15 July 2024 / Online: 16 July 2024 (04:25:15 CEST)
How to cite:
Szabo, D.; Ecsedy, M.; Szilagyi, Z.; Nagy, Z. Z.; Recsan, Z. Personalized Management of Patients With Proliferative Diabetic Vitreo-Retinopathy. Preprints2024, 2024071268. https://doi.org/10.20944/preprints202407.1268.v1
Szabo, D.; Ecsedy, M.; Szilagyi, Z.; Nagy, Z. Z.; Recsan, Z. Personalized Management of Patients With Proliferative Diabetic Vitreo-Retinopathy. Preprints 2024, 2024071268. https://doi.org/10.20944/preprints202407.1268.v1
Szabo, D.; Ecsedy, M.; Szilagyi, Z.; Nagy, Z. Z.; Recsan, Z. Personalized Management of Patients With Proliferative Diabetic Vitreo-Retinopathy. Preprints2024, 2024071268. https://doi.org/10.20944/preprints202407.1268.v1
APA Style
Szabo, D., Ecsedy, M., Szilagyi, Z., Nagy, Z. Z., & Recsan, Z. (2024). Personalized Management of Patients With Proliferative Diabetic Vitreo-Retinopathy. Preprints. https://doi.org/10.20944/preprints202407.1268.v1
Chicago/Turabian Style
Szabo, D., Zoltan Zsolt Nagy and Zsuzsanna Recsan. 2024 "Personalized Management of Patients With Proliferative Diabetic Vitreo-Retinopathy" Preprints. https://doi.org/10.20944/preprints202407.1268.v1
Abstract
Purpose: To evaluate prognostic factors for visual outcome in patients with diabetes who have undergone vitrectomy (PPV) for severe proliferative diabetic vitreo-retinopathy (PDVR) in at least one eye in the past 15 years. Methods: Medical records of 132 eyes of 66 patients were analyzed (median age 52ys 21-80; patients with type 1/2 diabetes 40/26, median follow-up 38 months 9-125). Correlation between final good visual outcome defined as 0.5≤ best corrected visual acuity (BCVA) and prognostic factors (age, sex, type and duration of diabetes, metabolic status, BCVA, diabetic retinopathy status, data of preoperative management, data of vitrectomy, postoperative complications) were analyzed. Results: BCVA improved significantly in the entire study cohort (from median 0.05 min-max 0.001-1 to 0.32 0.001-1, p <0.000). Visual stabilization was achieved in the majority of patients, and relatively good visual acuity (0.5≤BCVA) was maintained in more than one third of eyes. Multivariable GEE statistics showed that in addition to duration of diabetes and stable HbA1c values, only preoperative tractional macular detachment proved to be an independent significant predictor of visual outcome. Conclusions: Pars plana vitrectomy is a useful tool when performed early before tractional macular detachment. However, long-term visual stability can only be achieved with good metabolic control.
Keywords
proliferative diabetic retinopathy; pars plana vitrectomy; HbA1c; visual acuity; tractional macular detachment
Subject
Medicine and Pharmacology, Ophthalmology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
