Sakanoue, H.; Yamaji, H.; Okamoto, S.; Okano, K.; Fujita, Y.; Higashiya, S.; Murakami, T.; Hirohata, S.; Kusachi, S. Optimizing Activated Clotting Time Adjustment in Atrial Fibrillation Ablation: Necessity of Adjustments Across Different Measurement Methods. Preprints2024, 2024071361. https://doi.org/10.20944/preprints202407.1361.v1
APA Style
Sakanoue, H., Yamaji, H., Okamoto, S., Okano, K., Fujita, Y., Higashiya, S., Murakami, T., Hirohata, S., & Kusachi, S. (2024). Optimizing Activated Clotting Time Adjustment in Atrial Fibrillation Ablation: Necessity of Adjustments Across Different Measurement Methods. Preprints. https://doi.org/10.20944/preprints202407.1361.v1
Chicago/Turabian Style
Sakanoue, H., Satoshi Hirohata and Shozo Kusachi. 2024 "Optimizing Activated Clotting Time Adjustment in Atrial Fibrillation Ablation: Necessity of Adjustments Across Different Measurement Methods" Preprints. https://doi.org/10.20944/preprints202407.1361.v1
Abstract
Purpose
To compare and adjust activated clotting time (ACT) between two systems and to optimize ACT during atrial fibrillation (AF) ablation.
Methods
Electromagnetic detection using a rotation tube (EM system; Hemochron Response, Soma Tech Intl, Bloomfield, CT, USA) and photo-optical detection using a cartridge immersed in blood (PO system; ACT CA-300TM, APEL) were compared.
Results
The EM system showed an ACT of 320 ± 44 s (average ± 1 standard deviation), with a range of 156–487 s, from 3363 measurements in 1161 patients during uncomplicated procedures. An ACT >400 s was observed in 3.7% (124/3364) of patients. The pre-ablation ACT measured by the EM method was 143 ± 28 s. Cardiac tamponade was observed in 4/2085 ablations (0.19%) over 5 years. The ACT associated with cardiac tamponade ranged from 330 to 391 in the EM system. The regression equation was ACT-EM system = 1.19 × ACT-PO system + 9.03 (p
Medicine and Pharmacology, Cardiac and Cardiovascular Systems
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
