Review
Version 1
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Recent Advances in Non-Linear Imaging Techniques for Cancer Detection
Version 1
: Received: 18 July 2024 / Approved: 19 July 2024 / Online: 19 July 2024 (10:53:17 CEST)
How to cite: Ávila, F. J. Recent Advances in Non-Linear Imaging Techniques for Cancer Detection. Preprints 2024, 2024071569. https://doi.org/10.20944/preprints202407.1569.v1 Ávila, F. J. Recent Advances in Non-Linear Imaging Techniques for Cancer Detection. Preprints 2024, 2024071569. https://doi.org/10.20944/preprints202407.1569.v1
Abstract
The World Health Organization (WHO) cancer agency predicts that more than 35 mil-lion cases of will be experienced in 2050, a 77 % increase over the 2022 estimate. Cur-rently, the leading cancer diagnosed cancer are breast, lung and colorectal. There is no standardized tool for cancer diagnosis; initially clinical procedures are guided by the patient´s symptoms and generally involve biochemical blood tests, imaging and biopsy. Label-free nonlinear optical approaches are promising tool for tumor imaging, due to their inherent non-invasive biosafe contrast mechanisms and the ability to monitor collagen-related disorders and metabolic changes during cancer progression. Last ad-vances in nonlinear modalities for tumor imaging are reviewed here. In addition, an application of a blind deconvolution procedure to improve the quality of two-photon images of breast tumor tissues is shown.
Keywords
Cancer; tumor tissue; microwave imaging; two-photon excitation; second harmonic generation; third harmonic generation; Raman Scattering; Life-time two photon fluorescence; two-photon photodynamic therapy
Subject
Biology and Life Sciences, Life Sciences
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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