Version 1
: Received: 18 July 2024 / Approved: 19 July 2024 / Online: 19 July 2024 (08:15:21 CEST)
How to cite:
Chaudhary, R.; Tendero, S.; Olson, B.; Tumarinson, T. An Itch under the DRESS: A Vancomycin-Evoked Presentation in a Patient with Multiple Comorbidities. Preprints2024, 2024071578. https://doi.org/10.20944/preprints202407.1578.v1
Chaudhary, R.; Tendero, S.; Olson, B.; Tumarinson, T. An Itch under the DRESS: A Vancomycin-Evoked Presentation in a Patient with Multiple Comorbidities. Preprints 2024, 2024071578. https://doi.org/10.20944/preprints202407.1578.v1
Chaudhary, R.; Tendero, S.; Olson, B.; Tumarinson, T. An Itch under the DRESS: A Vancomycin-Evoked Presentation in a Patient with Multiple Comorbidities. Preprints2024, 2024071578. https://doi.org/10.20944/preprints202407.1578.v1
APA Style
Chaudhary, R., Tendero, S., Olson, B., & Tumarinson, T. (2024). An Itch under the DRESS: A Vancomycin-Evoked Presentation in a Patient with Multiple Comorbidities. Preprints. https://doi.org/10.20944/preprints202407.1578.v1
Chicago/Turabian Style
Chaudhary, R., Benajmin Olson and Taisiya Tumarinson. 2024 "An Itch under the DRESS: A Vancomycin-Evoked Presentation in a Patient with Multiple Comorbidities" Preprints. https://doi.org/10.20944/preprints202407.1578.v1
Abstract
A 70-year-old female with a significant medical history of hypertension, hypothyroidism, chronic back pain, and a left hip prosthetic joint infection experienced complications following a total hip replacement. After multiple revisions and eventual discharge to a rehabilitation facility, she developed surgical site bleeding and a femoral head dislocation extending into the pelvis. At our hospital, imaging revealed a failed hip arthroplasty with extensive damage and infection, necessitating complex revision surgery and an antibiotic regimen. During her treatment, she developed a diffuse rash diagnosed as vancomycin-induced hypersensitivity reaction (DRESS), prompting a switch to oral linezolid and systemic corticosteroids. Despite transient eosinophilia and elevated inflammatory markers, her condition stabilized, and she was discharged with instructions for follow-up. This case underscores the importance of vigilant monitoring and timely intervention in managing complex postoperative infections and drug reactions.
Medicine and Pharmacology, Epidemiology and Infectious Diseases
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
