PreprintArticleVersion 1This version is not peer-reviewed
Potential of a Low-iron Micronutrient Powder (MNP) for Prevention of Anemia in Children in a Low-iron Groundwater Setting: A Cross-sectional Study in Rural Bangladesh
Version 1
: Received: 25 July 2024 / Approved: 25 July 2024 / Online: 26 July 2024 (09:56:42 CEST)
How to cite:
Rahman, S.; Lee, P.; Biswas, N. U.; Khan, M. R.; Ahmed, F. Potential of a Low-iron Micronutrient Powder (MNP) for Prevention of Anemia in Children in a Low-iron Groundwater Setting: A Cross-sectional Study in Rural Bangladesh. Preprints2024, 2024072124. https://doi.org/10.20944/preprints202407.2124.v1
Rahman, S.; Lee, P.; Biswas, N. U.; Khan, M. R.; Ahmed, F. Potential of a Low-iron Micronutrient Powder (MNP) for Prevention of Anemia in Children in a Low-iron Groundwater Setting: A Cross-sectional Study in Rural Bangladesh. Preprints 2024, 2024072124. https://doi.org/10.20944/preprints202407.2124.v1
Rahman, S.; Lee, P.; Biswas, N. U.; Khan, M. R.; Ahmed, F. Potential of a Low-iron Micronutrient Powder (MNP) for Prevention of Anemia in Children in a Low-iron Groundwater Setting: A Cross-sectional Study in Rural Bangladesh. Preprints2024, 2024072124. https://doi.org/10.20944/preprints202407.2124.v1
APA Style
Rahman, S., Lee, P., Biswas, N. U., Khan, M. R., & Ahmed, F. (2024). Potential of a Low-iron Micronutrient Powder (MNP) for Prevention of Anemia in Children in a Low-iron Groundwater Setting: A Cross-sectional Study in Rural Bangladesh. Preprints. https://doi.org/10.20944/preprints202407.2124.v1
Chicago/Turabian Style
Rahman, S., Moududur Rahman Khan and Faruk Ahmed. 2024 "Potential of a Low-iron Micronutrient Powder (MNP) for Prevention of Anemia in Children in a Low-iron Groundwater Setting: A Cross-sectional Study in Rural Bangladesh" Preprints. https://doi.org/10.20944/preprints202407.2124.v1
Abstract
Iron supplementation is associated with side effects and thus reduces the intake compliance. Because it has fewer side effects, a recent trial recommended low-iron micronutrient powder (MNP) for the prevention of anemia in Bangladeshi children exposed to a high concentration of iron from drinking groundwater. In the present study, we hypothesize that the low-iron MNP is a potential intervention to prevent childhood anemia in the low groundwater-iron settings in Bangladesh. A cross-sectional study was conducted in Bangladesh with children aged 2-5 years who drank groundwater containing a low level of iron (0-<2 mg/L).The combined intake of iron was calculated from the key sources--diet, groundwater and MNPs. The intakes of iron were compared against the standard reference intake. The children’s hemoglobin was measured using a photometer. Combined intake of iron from dietary, groundwater and low-iron MNP in children was 5.8±2.0 and 6.9±2.5 mg/day comprising 193% and 169% of the Estimated Average Requirement in the 2-3 year-old and 4-5 year-old subgroups, respectively. Combined intake of bioavailable iron from dietary and groundwater sources was 0.42±0.023 and 0.22±0.019 mg/day in children exposed to groundwater concentration 0.8-<2.0 mg/L and 0.0-<0.8 mg/L respectively (p<0.001). The mean concentration of hemoglobin in the respective groups was 12.17±0.94 mg/dl and 11.91±0.91 mg/dl (p=0.30). The combined intake of iron from dietary and groundwater sources was associated with maintenance of hemoglobin concentration at the non-anemic level in most of the children. The finding highlights the potential of low-iron MNP in controlling childhood anemia in this setting.
Public Health and Healthcare, Public Health and Health Services
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
