Preprint Review Version 3 This version is not peer-reviewed

Challenges and Advances in Cervical Cancer Prevention for HIV-Positive Individuals

Version 1 : Received: 26 July 2024 / Approved: 28 July 2024 / Online: 30 July 2024 (09:18:17 CEST)
Version 2 : Received: 18 September 2024 / Approved: 19 September 2024 / Online: 19 September 2024 (11:47:05 CEST)
Version 3 : Received: 23 September 2024 / Approved: 24 September 2024 / Online: 24 September 2024 (12:30:08 CEST)

How to cite: Justiz-Vaillant, A.; Gopaul, D.; Asin-Milan, O.; Arrozarena-Fundora, R.; Thompson, R.; Soodeen, S.; Akpaka, P. E.; Unakal, C. Challenges and Advances in Cervical Cancer Prevention for HIV-Positive Individuals. Preprints 2024, 2024072238. https://doi.org/10.20944/preprints202407.2238.v3 Justiz-Vaillant, A.; Gopaul, D.; Asin-Milan, O.; Arrozarena-Fundora, R.; Thompson, R.; Soodeen, S.; Akpaka, P. E.; Unakal, C. Challenges and Advances in Cervical Cancer Prevention for HIV-Positive Individuals. Preprints 2024, 2024072238. https://doi.org/10.20944/preprints202407.2238.v3

Abstract

Human papillomavirus (HPV) is a well-known cause of cervical cancer, with HIV infection exacerbating the prevalence of high-risk HPV (HR-HPV) and cervical intraepithelial neoplasia (CIN). ART has been shown to reduce the likelihood of developing squamous intraepithelial lesions (SILs) and HR-HPV prevalence, although its impact on invasive cervical cancer remains inconclusive. In a study in Accra, 250 sexually active HIV-positive women exhibited a high HPV prevalence, emphasising the need for regular screening. HPV testing, visual inspection with acetic acid (VIA), and cytology-based tests are primary screening methods, each with specific advantages and limitations. Cervical cancer rates in sub-Saharan Africa are alarmingly high, necessitating targeted vaccination and prevention strategies.

Keywords

HIV; HPV; Prevalence; Vaccination strategy; HPV screening; Cervical intraepithelial neoplasia

Subject

Biology and Life Sciences, Virology

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