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Pd EnCat™ 30 Recycling in Suzuki Cross-Coupling Reactions
Version 1
: Received: 30 July 2024 / Approved: 31 July 2024 / Online: 2 August 2024 (09:30:50 CEST)
How to cite: D’Andrea, L.; Steinmann, C. Pd EnCat™ 30 Recycling in Suzuki Cross-Coupling Reactions. Preprints 2024, 2024072608. https://doi.org/10.20944/preprints202407.2608.v1 D’Andrea, L.; Steinmann, C. Pd EnCat™ 30 Recycling in Suzuki Cross-Coupling Reactions. Preprints 2024, 2024072608. https://doi.org/10.20944/preprints202407.2608.v1
Abstract
Pd EnCat™ 30 is a palladium catalyst broadly used in several hydrogenation and cross-coupling reactions. It is known for its numerous beneficial features, which include high-yielding performance, easy recovery, and reusability. However, the available data regarding its recyclability in Suzuki coupling reactions are limited to a few reaction cycles and, therefore, fail to explore its full potential. Our work focuses on investigating the extent of Pd EnCat™ 30 reusability in Suzuki cross-coupling reactions by measuring its performance according to isolated yields of product. Our findings demonstrate that Pd EnCat™ 30 can be reused over a minimum of 30 reaction cycles, which is advantageous in terms of cost reduction and more sustainable chemical production.
Keywords
Pd EnCat 30; catalyst recycling; Suzuki coupling; green chemistry; biaryl synthesis
Subject
Chemistry and Materials Science, Organic Chemistry
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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