Preprint Review Version 1 This version is not peer-reviewed

Bioactive Polysaccharides from Gracilaria lemaneiformis: Preparation, Structures, and Therapeutic Insights

Version 1 : Received: 31 July 2024 / Approved: 1 August 2024 / Online: 1 August 2024 (12:35:18 CEST)

How to cite: Wang, M.; Zhu, Z.; Wu, X.; Cheong, K.-L.; Li, X.; Yu, W.; Yao, Y.; Wu, J.; Cao, Z. Bioactive Polysaccharides from Gracilaria lemaneiformis: Preparation, Structures, and Therapeutic Insights. Preprints 2024, 2024080022. https://doi.org/10.20944/preprints202408.0022.v1 Wang, M.; Zhu, Z.; Wu, X.; Cheong, K.-L.; Li, X.; Yu, W.; Yao, Y.; Wu, J.; Cao, Z. Bioactive Polysaccharides from Gracilaria lemaneiformis: Preparation, Structures, and Therapeutic Insights. Preprints 2024, 2024080022. https://doi.org/10.20944/preprints202408.0022.v1

Abstract

Gracilaria lamaneiformis, a red seaweed, is an abundant source of bioactive polysaccharides with significant health-promoting properties. Nevertheless, the broad application of G. lamaneiformis in the nutraceutical and pharmaceutical sectors remains constrained due to the absence of comprehensive data. This review provides a detailed examination of the preparation methods, structural characteristics, and biological activities of G. lamaneiformis polysaccharides (GLP). We explore both conventional and advanced extraction techniques, highlighting the efficiency and yield improvements achieved through methods such as microwave-, ultrasonic-, and enzyme-assisted extraction. The structural elucidation of GLP using modern analytical techniques, including high-performance liquid chromatography, gas chromatography, and nuclear magnetic resonance spectroscopy, is discussed, providing comprehensive insights into their molecular composition and configuration. Furthermore, we critically evaluate the diverse biological activities of GLP, including their antioxidant, anti-inflammatory, antitumor, and gut microbiota modulation properties. This review underscores the therapeutic potential of GLP and suggests future research directions to fully harness their health benefits.

Keywords

Gracilaria lemaneiformis; polysaccharides; extraction; biological activities; gut microbiota

Subject

Biology and Life Sciences, Food Science and Technology

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