PreprintArticleVersion 1This version is not peer-reviewed
The Temporal Pattern of Change in Ionised Calcium, Parathyroid Hormone and Biomarkers of Bone Metabolism Following Ingestion of a Plant-Sourced Marine Multi-mineral + Plant-Sourced Protein Isolate in Healthy Young Adult Men and Women
Version 1
: Received: 1 August 2024 / Approved: 2 August 2024 / Online: 3 August 2024 (15:53:16 CEST)
How to cite:
Jakeman, P. M.; Kozior, M.; Demehin, O. A.; Ryan, M. M.; O'Connell, S. The Temporal Pattern of Change in Ionised Calcium, Parathyroid Hormone and Biomarkers of Bone Metabolism Following Ingestion of a Plant-Sourced Marine Multi-mineral + Plant-Sourced Protein Isolate in Healthy Young Adult Men and Women. Preprints2024, 2024080149. https://doi.org/10.20944/preprints202408.0149.v1
Jakeman, P. M.; Kozior, M.; Demehin, O. A.; Ryan, M. M.; O'Connell, S. The Temporal Pattern of Change in Ionised Calcium, Parathyroid Hormone and Biomarkers of Bone Metabolism Following Ingestion of a Plant-Sourced Marine Multi-mineral + Plant-Sourced Protein Isolate in Healthy Young Adult Men and Women. Preprints 2024, 2024080149. https://doi.org/10.20944/preprints202408.0149.v1
Jakeman, P. M.; Kozior, M.; Demehin, O. A.; Ryan, M. M.; O'Connell, S. The Temporal Pattern of Change in Ionised Calcium, Parathyroid Hormone and Biomarkers of Bone Metabolism Following Ingestion of a Plant-Sourced Marine Multi-mineral + Plant-Sourced Protein Isolate in Healthy Young Adult Men and Women. Preprints2024, 2024080149. https://doi.org/10.20944/preprints202408.0149.v1
APA Style
Jakeman, P. M., Kozior, M., Demehin, O. A., Ryan, M. M., & O'Connell, S. (2024). The Temporal Pattern of Change in Ionised Calcium, Parathyroid Hormone and Biomarkers of Bone Metabolism Following Ingestion of a Plant-Sourced Marine Multi-mineral + Plant-Sourced Protein Isolate in Healthy Young Adult Men and Women. Preprints. https://doi.org/10.20944/preprints202408.0149.v1
Chicago/Turabian Style
Jakeman, P. M., Michelle Mary Ryan and Shane O'Connell. 2024 "The Temporal Pattern of Change in Ionised Calcium, Parathyroid Hormone and Biomarkers of Bone Metabolism Following Ingestion of a Plant-Sourced Marine Multi-mineral + Plant-Sourced Protein Isolate in Healthy Young Adult Men and Women" Preprints. https://doi.org/10.20944/preprints202408.0149.v1
Abstract
An increase in plant-sourced (PS) nutrient intake is promoted in support of a sustainable diet. PS dietary minerals and proteins have bioactive properties that can affect bone health and the risk of fracture. In a group randomised, cross-over, design, this study evaluated the post-ingestion, temporal pattern of change in arterialised ionised calcium (iCa), parathyroid hormone (PTH), C-terminal crosslinked telopeptide of type I collagen (CTX) and procollagen type 1 amino-terminal propeptide (P1NP) for 4 hours following ingestion of a novel supplement (SUPP) containing a PS marine multi-mineral + PS protein isolate. A diurnally matched intake of mineral water was used as a control (CON). Compared to baseline, the change in iCa concentration was 0.022 (95%CI, 0.006 to 0.038, p = 0.011) mmol/l greater in SUPP than CON, resulting in a -4.214 (95%CI, -8.244 to -.183, p = 0.042) pg/mL mean reduction in PTH, a -0.64 (95%CI, -0.199 to -0.008, p = .029) ng/mL decrease in the biomarker of bone resorption, CTX, and no change in biomarker of bone formation, P1NP. Used as a dietary supplement, or by incorporation into a food matrix, the promotion of PS marine multi-mineral and PS protein isolates may contribute to a more sustainable diet and overall bone health.
Keywords
Sustainable diet; plant mineral; plant protein; bone health; postprandial; young adults
Subject
Biology and Life Sciences, Food Science and Technology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
