Preprint Case Report Version 1 This version is not peer-reviewed

Successful Extracorporeal Membrane Oxygenation Treatment in a Newly Diagnosed HIV Positive and Acquired Immune Defi-Ciency Syndrome (Aids) Patient with Acute Respiratory Distress Syndrome (Ards) Complicated by Pneumocystis and Cytomeg-Alovirus Pneumo

Version 1 : Received: 2 August 2024 / Approved: 2 August 2024 / Online: 5 August 2024 (09:31:40 CEST)

How to cite: Kang, J. K.; Acton, M.; Kim, B. S. Successful Extracorporeal Membrane Oxygenation Treatment in a Newly Diagnosed HIV Positive and Acquired Immune Defi-Ciency Syndrome (Aids) Patient with Acute Respiratory Distress Syndrome (Ards) Complicated by Pneumocystis and Cytomeg-Alovirus Pneumo. Preprints 2024, 2024080215. https://doi.org/10.20944/preprints202408.0215.v1 Kang, J. K.; Acton, M.; Kim, B. S. Successful Extracorporeal Membrane Oxygenation Treatment in a Newly Diagnosed HIV Positive and Acquired Immune Defi-Ciency Syndrome (Aids) Patient with Acute Respiratory Distress Syndrome (Ards) Complicated by Pneumocystis and Cytomeg-Alovirus Pneumo. Preprints 2024, 2024080215. https://doi.org/10.20944/preprints202408.0215.v1

Abstract

We report a case of an adult patient with newly diagnosed human immunodeficiency virus (HIV) infection, Acquired Immune Deficiency Syndrome (AIDS), and acute respiratory distress syndrome (ARDS) secondary to pneumocystis and cytomegalovirus pneumonia present on presentation that was successfully managed with veno-venous extracorporeal membrane oxygenation (VV-ECMO). A 40-year-old female with a past medical history of asthma was admitted to a local hospital due to dyspnea, cough, and wheezing where she was diagnosed with HIV infection, ARDS, and combined pneumocystis and cytomegalovirus pneumonia. Her pulmonary function quickly declined neces-sitating mechanical ventilation (MV). After she failed all conventional therapies, she was trans-ferred to a tertiary medical center for VV-ECMO therapy. Patient was successfully treated with antiretroviral therapy (ART), antibiotics, antivirals, steroids, and 48 days of VV-ECMO support, with complete resolution of her respiratory symptoms. She was discharged on hospital day 82. HIV positive patients with ARDS complicated by opportunistic pulmonary infections can be successfully managed with ART, appropriate anti-infective therapies, and VV-ECMO.

Keywords

VV-ECMO; ARDS; HIV; AIDS; PJP; CMV; ART

Subject

Medicine and Pharmacology, Surgery

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