Version 1
: Received: 9 August 2024 / Approved: 12 August 2024 / Online: 12 August 2024 (14:11:36 CEST)
How to cite:
Robak, T.; Braun, M.; Janus, A.; Guminska, A.; Robak, E. Rare Clinical Symptoms in Hairy Cell Leukemia – an Overview. Preprints2024, 2024080812. https://doi.org/10.20944/preprints202408.0812.v1
Robak, T.; Braun, M.; Janus, A.; Guminska, A.; Robak, E. Rare Clinical Symptoms in Hairy Cell Leukemia – an Overview. Preprints 2024, 2024080812. https://doi.org/10.20944/preprints202408.0812.v1
Robak, T.; Braun, M.; Janus, A.; Guminska, A.; Robak, E. Rare Clinical Symptoms in Hairy Cell Leukemia – an Overview. Preprints2024, 2024080812. https://doi.org/10.20944/preprints202408.0812.v1
APA Style
Robak, T., Braun, M., Janus, A., Guminska, A., & Robak, E. (2024). Rare Clinical Symptoms in Hairy Cell Leukemia – an Overview. Preprints. https://doi.org/10.20944/preprints202408.0812.v1
Chicago/Turabian Style
Robak, T., Anna Guminska and Ewa Robak. 2024 "Rare Clinical Symptoms in Hairy Cell Leukemia – an Overview" Preprints. https://doi.org/10.20944/preprints202408.0812.v1
Abstract
Abstract: Background: Hairy cell leukemia (HCL) is a rare indolent B-cell lymphoid malignancy. The majority of patients are asymptomatic and HCL is usually diagnosed incidentally during a routine blood cell counts. In symptomatic patients, typical symptoms are related to pancytope-nia and splenomegaly. In this review we present, rare clinical symptoms in patients with HCL. Methods: A literature search was conducted of PubMed, Web of Science, and Google Scholar for articles concerning hairy cell leukemia, leukemia cutis, bone lesions, neurological manifesta-tions, pulmonary symptoms, ocular manifestations, cardiac manifestation, rare symptoms. Publications from January 1980 to August 2024 were scrutinized. Additional relevant publica-ions were obtained by reviewing the references from the chosen articles. Results: Extra medul-lary and extra nodal manifestations of classic HCL are rare. However, leukemic involvement in the skin, bone, central nervous system, gastrointestinal tract, heart, kidney, liver, lung, ocular and other organs have been reported.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
