Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Leveraging Functional Genomics for Understanding Beef Quality Complexities and Breeding Beef Cattle for Improved Meat Quality

Version 1 : Received: 14 August 2024 / Approved: 14 August 2024 / Online: 15 August 2024 (03:17:19 CEST)

How to cite: Tian, R.; Mahmoodi, M.; Tian, J.; Esmailizadeh Koshkoiyeh, S.; Zhao, M.; Saminzadeh, M.; Li, H.; Wang, X.; Li, Y.; Esmailizadeh, A. Leveraging Functional Genomics for Understanding Beef Quality Complexities and Breeding Beef Cattle for Improved Meat Quality. Preprints 2024, 2024081038. https://doi.org/10.20944/preprints202408.1038.v1 Tian, R.; Mahmoodi, M.; Tian, J.; Esmailizadeh Koshkoiyeh, S.; Zhao, M.; Saminzadeh, M.; Li, H.; Wang, X.; Li, Y.; Esmailizadeh, A. Leveraging Functional Genomics for Understanding Beef Quality Complexities and Breeding Beef Cattle for Improved Meat Quality. Preprints 2024, 2024081038. https://doi.org/10.20944/preprints202408.1038.v1

Abstract

Consumer perception of beef is heavily influenced by overall meat quality, a critical factor in the cattle industry. Genomics has the potential to improve important beef quality traits and identify genetic markers and causal variants associated with these traits by genomic selection (GS), and genome-wide association studies (GWAS) approaches. Transcriptomics, proteomics, and metabolomics provide insights into underlying genetic mechanisms by identifying differentially expressed genes, proteins, and metabolic pathways linked to quality traits, complementing GWAS data. Leveraging these functional genomics techniques can optimize beef cattle breeding for enhanced quality traits to meet high-quality beef demand. This paper provides a comprehensive overview of the current state applications of the omics technologies in uncovering functional variants underlying beef quality complexities. By highlighting the latest findings from GWAS, GS, transcriptomics, proteomics, and metabolomics studies, this work seeks to serve as a valuable resource fostering a deeper understanding of the complex relationships between genetics, gene expression, protein dynamics, and metabolic pathways in shaping beef quality.

Keywords

Beef Cattle; Functional Genomics; Genomic Selection; GWAS; Meat quality; Molecular Breeding; Omics Technologies.

Subject

Biology and Life Sciences, Animal Science, Veterinary Science and Zoology

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