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Prevalence and Risk Factors of Renal Artery Stenosis in Patients Undergoing Simultaneous Coronary and Renal Artery Angiography: A Systematic Review and Meta-Analysis of 31,689 Patients from 31 Study
Version 1
: Received: 15 August 2024 / Approved: 15 August 2024 / Online: 20 August 2024 (04:03:36 CEST)
How to cite:
Schwarz, K.; Straume Bah, I.; Will, M.; Kwok, C. S.; Mascherbauer, J.; Kumric, M.; Bozic, J.; Borovac, J. A. Prevalence and Risk Factors of Renal Artery Stenosis in Patients Undergoing Simultaneous Coronary and Renal Artery Angiography: A Systematic Review and Meta-Analysis of 31,689 Patients from 31 Study. Preprints2024, 2024081172. https://doi.org/10.20944/preprints202408.1172.v1
Schwarz, K.; Straume Bah, I.; Will, M.; Kwok, C. S.; Mascherbauer, J.; Kumric, M.; Bozic, J.; Borovac, J. A. Prevalence and Risk Factors of Renal Artery Stenosis in Patients Undergoing Simultaneous Coronary and Renal Artery Angiography: A Systematic Review and Meta-Analysis of 31,689 Patients from 31 Study. Preprints 2024, 2024081172. https://doi.org/10.20944/preprints202408.1172.v1
Schwarz, K.; Straume Bah, I.; Will, M.; Kwok, C. S.; Mascherbauer, J.; Kumric, M.; Bozic, J.; Borovac, J. A. Prevalence and Risk Factors of Renal Artery Stenosis in Patients Undergoing Simultaneous Coronary and Renal Artery Angiography: A Systematic Review and Meta-Analysis of 31,689 Patients from 31 Study. Preprints2024, 2024081172. https://doi.org/10.20944/preprints202408.1172.v1
APA Style
Schwarz, K., Straume Bah, I., Will, M., Kwok, C. S., Mascherbauer, J., Kumric, M., Bozic, J., & Borovac, J. A. (2024). Prevalence and Risk Factors of Renal Artery Stenosis in Patients Undergoing Simultaneous Coronary and Renal Artery Angiography: A Systematic Review and Meta-Analysis of 31,689 Patients from 31 Study. Preprints. https://doi.org/10.20944/preprints202408.1172.v1
Chicago/Turabian Style
Schwarz, K., Josko Bozic and Josip Andelo Borovac. 2024 "Prevalence and Risk Factors of Renal Artery Stenosis in Patients Undergoing Simultaneous Coronary and Renal Artery Angiography: A Systematic Review and Meta-Analysis of 31,689 Patients from 31 Study" Preprints. https://doi.org/10.20944/preprints202408.1172.v1
Abstract
Background/Objectives: RAS is associated with coronary artery disease (CAD), exacerbation of arterial hypertension and progression to heart failure, but remains frequently unrecognised in clinical practice. Methods: We conducted a systematic review and meta-analysis of studies by pooling data of patients undergoing CAG due to suspected or stable CAD that received a bilateral renal artery angiography; Results: A total of 31 studies with 31,689 patients were included (mean age 63.2±8.7 years, 20.9% were female). Overall, 13.4% (95%CI 10.5-16.7%) of patients undergoing coronary angiography had significant RAS, with 6.5% (95% CI 4.5-8.9%) and 3.7% (95%CI 2.5-5.2%) having severe and bilateral RAS. The mean weighted proportion of patients with 3-vessel coronary disease (3VD) was 25.1 (95%CI 19.6-30.9%) while 4.2% (95%CI 2.6-6.2%) had leftmain (LM) coronary disease. Patients with RAS compared to those without RAS were significantly older (mean difference - MD 4.2 years, (95%CI 3.8-4.6). The relative risk of RAS was greater for the female sex (risk ratio, 95%CI; RR 1.3, 1.03-1.57), presence of diabetes (RR 1.2, 1.10-1.36), arterial hypertension (RR 1.3, 1.21-1.46), dyslipidemia (RR 1.1, 1.06-1.14), peripheral artery disease-PAD (RR 2.1, 1.40-3.16), chronic kidney disease-CKD (RR 2.6, 2.04-3.37), 3VD (RR 1.6, 1.30-1.87), and LM disease (RR 1.8, 1.28-2.47). Smoking had a neutral effect on the risk of RAS occurrence (RR 1.0, 0.94-1.06); Conclusions: RAS is common in patients undergoing coronary angiography. CKD, PAD, older age, and severe CAD were among the strongest predictors for the presence of significant RAS.
Medicine and Pharmacology, Cardiac and Cardiovascular Systems
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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