Version 1
: Received: 19 August 2024 / Approved: 19 August 2024 / Online: 20 August 2024 (10:54:14 CEST)
How to cite:
Anueyiagu, K. N.; Agu, C. G.; Umar, U.; Lopes, B. S. Antimicrobial Resistance in Diverese Escherichia coli Pathotypes from Nigeria. Preprints2024, 2024081429. https://doi.org/10.20944/preprints202408.1429.v1
Anueyiagu, K. N.; Agu, C. G.; Umar, U.; Lopes, B. S. Antimicrobial Resistance in Diverese Escherichia coli Pathotypes from Nigeria. Preprints 2024, 2024081429. https://doi.org/10.20944/preprints202408.1429.v1
Anueyiagu, K. N.; Agu, C. G.; Umar, U.; Lopes, B. S. Antimicrobial Resistance in Diverese Escherichia coli Pathotypes from Nigeria. Preprints2024, 2024081429. https://doi.org/10.20944/preprints202408.1429.v1
APA Style
Anueyiagu, K. N., Agu, C. G., Umar, U., & Lopes, B. S. (2024). Antimicrobial Resistance in Diverese Escherichia coli Pathotypes from Nigeria. Preprints. https://doi.org/10.20944/preprints202408.1429.v1
Chicago/Turabian Style
Anueyiagu, K. N., Uzal Umar and Bruno Silvester Lopes. 2024 "Antimicrobial Resistance in Diverese Escherichia coli Pathotypes from Nigeria" Preprints. https://doi.org/10.20944/preprints202408.1429.v1
Abstract
Escherichia coli is a gram-negative commensal bacterium living in human and animal intestines. Its pathogenic strains are cause of high morbidity which can adversely affect people by causing urinary tract infections, food poisoning, septic shock, or meningitis. Humans can contract E. coli by eating contaminated food—such as raw or undercooked raw milk, meat products, and fresh produce sold in open markets—as well as by coming into contact with contaminated settings like wastewater, municipal water, soil, and faeces. Some pathogenic strains of E. coli have been identified in Nigeria such as enterohemorrhagic (EHEC), as well as enterotoxigenic (ETEC), enteropathogenic (EPEC), enteroinvasive (EIEC), enteroaggregative (EAEC), and verotoxigenic (VTEC). This causes acute watery or bloody diarrhoea, stomach cramps, and vomiting. Apart from the virulence profile of E. coli, antibiotic resistance mechanisms such as the presence of blaCTX-M found in humans, animals and environmental isolates which are of great importance and require surveillance and monitoring for emerging threats in resource-limited countries. This review is aimed at understanding the underlying mechanisms of evolution and antibiotic resistance in E. coli in Nigeria and highlighting the use of improving One Health approaches to combat the problem of emerging infectious diseases.
Keywords
Escherichia coli; E. coli O157:H7; Shiga-toxins; antimicrobial resistance; STEC; Diarrheagenic E. Coli; blaCTX-M; ESBL
Subject
Biology and Life Sciences, Immunology and Microbiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
