PreprintArticleVersion 1This version is not peer-reviewed
Clinical Significance of Para-Aortic Node Metastasis for Prognosis in Patients with Pancreaticobiliary Duct Carcinoma Who Underwent Radical Surgical Resections
Nanashima, A.; Arai, J.; Hiyoshi, M.; Imamura, N.; Hamada, T.; Tsuchimochi, Y.; Wada, T.; Shimizu, I.; Ochiai, T.; Kawakami, H.; Sato, Y. Clinical Significance of Para-Aortic Node Metastasis for Prognosis in Patients with Pancreaticobiliary Duct Carcinoma Who Underwent Radical Surgical Resections. Preprints2024, 2024081526. https://doi.org/10.20944/preprints202408.1526.v1
APA Style
Nanashima, A., Arai, J., Hiyoshi, M., Imamura, N., Hamada, T., Tsuchimochi, Y., Wada, T., Shimizu, I., Ochiai, T., Kawakami, H., & Sato, Y. (2024). Clinical Significance of Para-Aortic Node Metastasis for Prognosis in Patients with Pancreaticobiliary Duct Carcinoma Who Underwent Radical Surgical Resections. Preprints. https://doi.org/10.20944/preprints202408.1526.v1
Chicago/Turabian Style
Nanashima, A., Hiroshi Kawakami and Yuichiro Sato. 2024 "Clinical Significance of Para-Aortic Node Metastasis for Prognosis in Patients with Pancreaticobiliary Duct Carcinoma Who Underwent Radical Surgical Resections" Preprints. https://doi.org/10.20944/preprints202408.1526.v1
Abstract
Background: We investigated the significance of the para-aortic node (PALN) and other regional node metastases (RLN), reflecting malignant histological findings or poor patient prognosis, in patients with biliary duct cancers (BDC) and pancreatic carcinomas (PC) who underwent radical resections at two institutes. Methods: Conventional clinicopathological factors, including metastasis to the PALN and RLN, and surgical outcomes or long-term prognosis in 181 PC and 116 BDC patients between 1994 and 2022 were examined. Results: In patients with PC, cancer metastasis was observed in the RLN and PALN in 54% and 9% of patients, respectively. In patients with BDC, cancer metastasis was observed in the RLN and PALN in 39% and 9% of patients, respectively. Disease-free survival (DFS) and overall survival (OS) in patients with BDC and PALN metastasis were significantly lower than those without PALN metastasis; however, several patients survived over three years. Multivariate analysis revealed that, in patients with BDC, PALN metastasis was an independently related factor of OS, and RLN was an independently related factor for DFS, respectively (p
Medicine and Pharmacology, Gastroenterology and Hepatology
Copyright:
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