Preprint Article Version 1 This version is not peer-reviewed

Are There Co-variations between Herpes Simplex Virus Status and Oral Risk Habits in a Cohort of Sri Lankan Male Oral Fibroepithelial Polyp Patients?: Findings from a Preliminary Study

Version 1 : Received: 28 August 2024 / Approved: 28 August 2024 / Online: 29 August 2024 (03:12:58 CEST)

How to cite: Perera, M.; Perera, I. Are There Co-variations between Herpes Simplex Virus Status and Oral Risk Habits in a Cohort of Sri Lankan Male Oral Fibroepithelial Polyp Patients?: Findings from a Preliminary Study. Preprints 2024, 2024082070. https://doi.org/10.20944/preprints202408.2070.v1 Perera, M.; Perera, I. Are There Co-variations between Herpes Simplex Virus Status and Oral Risk Habits in a Cohort of Sri Lankan Male Oral Fibroepithelial Polyp Patients?: Findings from a Preliminary Study. Preprints 2024, 2024082070. https://doi.org/10.20944/preprints202408.2070.v1

Abstract

The relationship between Herpes Simplex Virus (HSV) and oral risk habits is still uncertain. This study aimed to investigate the connection between oral risk habits and HSV status in a group of male patients from Sri Lanka who have oral fibroepithelial polyps. We collected 25 fibroepithelial polyps from nine oro-maxillofacial units in six provinces of Sri Lanka. Tissue samples were taken from frozen excisional biopsies to avoid contamination and tested for HSV- DNA using a real-time PCR assay. The results showed that HSV-DNA was present in 44% of the samples, with 66.67% being HSV-1 and 33.33% being HSV-2. However, there was no significant correlation between HSV status and oral risk habits such as betel quid chewing, smoking, and alcohol abuse. The study suggests the need for larger case-control studies to determine any significant associations between different types of Herpes Simplex Virus and oral risk habits.

Keywords

Herpes Simplex Virus; Oral Risk Habits; Asymptomatic; Latency

Subject

Biology and Life Sciences, Virology

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