Version 1
: Received: 1 September 2024 / Approved: 2 September 2024 / Online: 2 September 2024 (09:49:45 CEST)
How to cite:
Ferrari, I. V. Molecular Docking Study Reveals Amentoflavone as a Potential Inhibitor of Dengue Virus Envelope Protein. Preprints2024, 2024090083. https://doi.org/10.20944/preprints202409.0083.v1
Ferrari, I. V. Molecular Docking Study Reveals Amentoflavone as a Potential Inhibitor of Dengue Virus Envelope Protein. Preprints 2024, 2024090083. https://doi.org/10.20944/preprints202409.0083.v1
Ferrari, I. V. Molecular Docking Study Reveals Amentoflavone as a Potential Inhibitor of Dengue Virus Envelope Protein. Preprints2024, 2024090083. https://doi.org/10.20944/preprints202409.0083.v1
APA Style
Ferrari, I. V. (2024). Molecular Docking Study Reveals Amentoflavone as a Potential Inhibitor of Dengue Virus Envelope Protein. Preprints. https://doi.org/10.20944/preprints202409.0083.v1
Chicago/Turabian Style
Ferrari, I. V. 2024 "Molecular Docking Study Reveals Amentoflavone as a Potential Inhibitor of Dengue Virus Envelope Protein" Preprints. https://doi.org/10.20944/preprints202409.0083.v1
Abstract
Dengue virus infection poses a significant global health threat, particularly in tropical and subtropical regions. In this study, we employed molecular docking techniques to investigate potential inhibitors of Dengue virus type 1 envelope protein. Through a series of docking simulations, we identified Amentoflavone as a promising candidate with favorable binding affinity. Our results indicate that Amentoflavone exhibited a binding energy of -10 kcal/mol, suggesting strong interaction with the target protein. These findings highlight the potential of Amentoflavone as a therapeutic agent for combating Dengue virus infection. Further experimental validation is warranted to confirm its efficacy and safety profile. This study underscores the utility of in silico approaches in drug discovery and development against emerging infectious diseases like Dengue.
Biology and Life Sciences, Immunology and Microbiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
