Bromelain: Unveiling Its Potential as a Natural Anti-inflammatory Agent through Effective Binding to Apoptosis-Associated Speck-Like Containing CARD (ASC)

Ivan ferrari

doi:10.20944/preprints202409.0132.v1

Preprint Article Version 1 This version is not peer-reviewed

Version 1 : Received: 1 September 2024 / Approved: 2 September 2024 / Online: 3 September 2024 (10:59:04 CEST)

This theoretical study presents a novel perspective on the potential anti-inflammatory properties of Bromelain, a natural agent extracted from pineapple stems. The investigation explores the binding capabilities of Bromelain to Apoptosis-associated speck-like containing CARD (ASC), a crucial adapter molecule known for its involvement in inflammatory processes and inflammasome formation. For the first time, these findings suggest that Bromelain exhibits a notable affinity for ASC, indicating its promising role as a natural anti-inflammatory agent. This study sheds light on the molecular interactions that may contribute to Bromelain's therapeutic potential in modulating inflammatory responses.

Apoptosis-associated speck-like containing; Bromelain; HDOCK SERVER

Biology and Life Sciences, Biochemistry and Molecular Biology

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Bromelain: Unveiling Its Potential as a Natural Anti-inflammatory Agent through Effective Binding to Apoptosis-Associated Speck-Like Containing CARD (ASC)

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