Version 1
: Received: 3 September 2024 / Approved: 3 September 2024 / Online: 4 September 2024 (08:36:17 CEST)
How to cite:
Nagamatsu, Y.; Ikeda, H.; Nagamatsu, H. Long-term Storage Stability of Neutral Electrolyzed Water by Two-stage Electrolysis: Optimal Storage Conditions for Intraoral Use. Preprints2024, 2024090302. https://doi.org/10.20944/preprints202409.0302.v1
Nagamatsu, Y.; Ikeda, H.; Nagamatsu, H. Long-term Storage Stability of Neutral Electrolyzed Water by Two-stage Electrolysis: Optimal Storage Conditions for Intraoral Use. Preprints 2024, 2024090302. https://doi.org/10.20944/preprints202409.0302.v1
Nagamatsu, Y.; Ikeda, H.; Nagamatsu, H. Long-term Storage Stability of Neutral Electrolyzed Water by Two-stage Electrolysis: Optimal Storage Conditions for Intraoral Use. Preprints2024, 2024090302. https://doi.org/10.20944/preprints202409.0302.v1
APA Style
Nagamatsu, Y., Ikeda, H., & Nagamatsu, H. (2024). Long-term Storage Stability of Neutral Electrolyzed Water by Two-stage Electrolysis: Optimal Storage Conditions for Intraoral Use. Preprints. https://doi.org/10.20944/preprints202409.0302.v1
Chicago/Turabian Style
Nagamatsu, Y., Hiroshi Ikeda and Hiroshi Nagamatsu. 2024 "Long-term Storage Stability of Neutral Electrolyzed Water by Two-stage Electrolysis: Optimal Storage Conditions for Intraoral Use" Preprints. https://doi.org/10.20944/preprints202409.0302.v1
Abstract
Electrolyzed water, which mainly contains hypochlorous acid, is widely used because of its strong microbicidal effects, biosafety, and eco-friendliness. For frequent use in intraoral treatments, we focused on neutral electrolyzed water (NW) produced using two-stage electrolysis and investigated its storage stability. For standard-concentration NWs with free available chlorine concentration (ACC) of 25, 35, and 50 mg/L and high-concentration NWs (100, 200, 300, 500, and 1000 mg/L), changes in the pH, oxidation-reduction potential, and ACC during 126 days of storage and the bactericidal efficacies were examined. Storage under non-shaded conditions at room temperature (LRT) and a higher ACC substantially altered the properties of the NW. NW (≤ 300 mg/L) had a pH of 5.9–7.3 even after storage under LRT; however, NW with higher ACC (500 and 1000 mg/L) had a pH ˂ 5.5, critical for human enamel), even under shaded and refrigerated conditions (SLW). Only NW (25 mg/L) stored under LRT exhibited the lowest ACC (5 mg/L), indicating a decreased bactericidal effect. When stored for use in intraoral treatments, NWs should be prepared with an ACC of 25–300 mg/L and stored in SLW. If diluted NW is used, the ACC should be checked and appropriately diluted every time.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
