Version 1
: Received: 3 September 2024 / Approved: 4 September 2024 / Online: 5 September 2024 (00:27:18 CEST)
How to cite:
Edison, L. K.; Kudva, I. T.; Kariyawasam, S. Host-Pathogen Interactions during STEC Adherence and Colonization in the Bovine Gut: A Comprehensive Review. Preprints2024, 2024090379. https://doi.org/10.20944/preprints202409.0379.v1
Edison, L. K.; Kudva, I. T.; Kariyawasam, S. Host-Pathogen Interactions during STEC Adherence and Colonization in the Bovine Gut: A Comprehensive Review. Preprints 2024, 2024090379. https://doi.org/10.20944/preprints202409.0379.v1
Edison, L. K.; Kudva, I. T.; Kariyawasam, S. Host-Pathogen Interactions during STEC Adherence and Colonization in the Bovine Gut: A Comprehensive Review. Preprints2024, 2024090379. https://doi.org/10.20944/preprints202409.0379.v1
APA Style
Edison, L. K., Kudva, I. T., & Kariyawasam, S. (2024). Host-Pathogen Interactions during STEC Adherence and Colonization in the Bovine Gut: A Comprehensive Review. Preprints. https://doi.org/10.20944/preprints202409.0379.v1
Chicago/Turabian Style
Edison, L. K., Indira T Kudva and Subhashinie Kariyawasam. 2024 "Host-Pathogen Interactions during STEC Adherence and Colonization in the Bovine Gut: A Comprehensive Review" Preprints. https://doi.org/10.20944/preprints202409.0379.v1
Abstract
Shiga toxin-producing Escherichia coli (STEC) is a significant public health threat due to its ability to cause severe gastrointestinal diseases in humans, ranging from diarrhea to life-threatening conditions such as hemorrhagic colitis and hemolytic uremic syndrome (HUS). As the primary reservoir of STEC, cattle play a crucial role in its transmission through contaminated food and water, posing a considerable risk to human health. This comprehensive review explores host-pathogen interactions during STEC colonization of the bovine gut, focusing on the role of gut microbiota in modulating these interactions and influencing disease outcomes. We integrated findings from published transcriptomics, proteomics, and genomics studies to provide a thorough understanding of how STEC adheres to and colonizes the bovine gastrointestinal tract. The insights from this review offer potential avenues for the development of novel preventative and therapeutic strategies aimed at controlling STEC colonization in cattle threby reducing the risk of zoonotic transmission.
Keywords
Zoonotic transmission; food safety; public health; virulence factors
Subject
Public Health and Healthcare, Public, Environmental and Occupational Health
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
