Version 1
: Received: 15 September 2024 / Approved: 16 September 2024 / Online: 16 September 2024 (09:59:47 CEST)
How to cite:
Zhuang, Y.; Zhang, Y.; Liu, C.; Zhong, Y. Interplay Between the Circadian Clock and Sirtuins. Preprints2024, 2024091202. https://doi.org/10.20944/preprints202409.1202.v1
Zhuang, Y.; Zhang, Y.; Liu, C.; Zhong, Y. Interplay Between the Circadian Clock and Sirtuins. Preprints 2024, 2024091202. https://doi.org/10.20944/preprints202409.1202.v1
Zhuang, Y.; Zhang, Y.; Liu, C.; Zhong, Y. Interplay Between the Circadian Clock and Sirtuins. Preprints2024, 2024091202. https://doi.org/10.20944/preprints202409.1202.v1
APA Style
Zhuang, Y., Zhang, Y., Liu, C., & Zhong, Y. (2024). Interplay Between the Circadian Clock and Sirtuins. Preprints. https://doi.org/10.20944/preprints202409.1202.v1
Chicago/Turabian Style
Zhuang, Y., Chao Liu and Yingbin Zhong. 2024 "Interplay Between the Circadian Clock and Sirtuins" Preprints. https://doi.org/10.20944/preprints202409.1202.v1
Abstract
The circadian clock is an autonomous timekeeping system evolved by organisms to adapt to external changes, regulating a variety of important physiological and behavioral processes. Recent studies have shown that the sirtuin family of histone deacetylases is involved in regulating the expression of clock genes and plays an important role in maintaining the normal rhythm of clock gene expression and behavior. Moreover, sirtuins are regulated directly or indirectly by the circadian clock system. The mutual regulation between the circadian clock and sirtuins is likely involved in a variety of signal transduction and metabolism processes. In this review, we discuss the molecular mechanisms and research progress on the intertwined relationship between the circadian clock and sirtuins, highlighting sirtuins as molecular links between metabolic control and circadian rhythms and offering our perspectives on future developments in the field.
Biology and Life Sciences, Biochemistry and Molecular Biology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
