Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Anomaly Detection in Individual Specific Networks through Explainable Generative Adversarial Attributed Networks

Version 1 : Received: 19 September 2024 / Approved: 19 September 2024 / Online: 23 September 2024 (13:39:28 CEST)

How to cite: Guzzi, P. H.; Lomoio, U.; Mazza, T.; Veltri, P. Anomaly Detection in Individual Specific Networks through Explainable Generative Adversarial Attributed Networks. Preprints 2024, 2024091565. https://doi.org/10.20944/preprints202409.1565.v1 Guzzi, P. H.; Lomoio, U.; Mazza, T.; Veltri, P. Anomaly Detection in Individual Specific Networks through Explainable Generative Adversarial Attributed Networks. Preprints 2024, 2024091565. https://doi.org/10.20944/preprints202409.1565.v1

Abstract

Recently, the availability of many omics data source has given the rise of modelling biological networks for each individual or patient. Such networks are able to represent individual-specific characteristics, providing insights into the condition of each person. Given a set of networks of individuals, a network representing a particular condition (e.g., an individual with a specific disease) may be seen as an anomaly network. Consequently, the use of Graph Anomaly Detection techniques may support such analysis. Among the others, Generative Adversarial Networks present optimal per- formances in anomaly detection. This paper presents ADIN (Anomaly Detection in Individual Networks), a framework based on Generative Adversarial Attributed Networks (GAANs) for anomaly detection in convergence/divergence patients at- tributed networks. Preliminary results on networks generated from computational biology gene expression data demonstrate the effectiveness of our approach in detecting and explaining bladder cancer patients.

Keywords

ISN; GANN; Patient

Subject

Computer Science and Mathematics, Artificial Intelligence and Machine Learning

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