Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Combination Therapy for Multi-Drug-Resistant Mycoplasma genitalium

Version 1 : Received: 20 September 2024 / Approved: 21 September 2024 / Online: 24 September 2024 (03:49:18 CEST)

How to cite: Kenyon, C. Combination Therapy for Multi-Drug-Resistant Mycoplasma genitalium. Preprints 2024, 2024091671. https://doi.org/10.20944/preprints202409.1671.v1 Kenyon, C. Combination Therapy for Multi-Drug-Resistant Mycoplasma genitalium. Preprints 2024, 2024091671. https://doi.org/10.20944/preprints202409.1671.v1

Abstract

In Belgium, around a quarter of M. genitalium infections are resistant to both macrolides and fluoroquinolones -termed multi-drug-resistant (MDR) infections. It is unclear what the best treatment is for these infections. We report the first two cases of MDR M. genitalium urethritis treated with combination therapy of minocycline, metronidazole, methenamine and pristinamycin. In both cases, this treatment resulted in microbiological and clinical cure.

Keywords

M. genitalium; minocycline; metronidazole; methenamine; pristinamycin; AMR

Subject

Medicine and Pharmacology, Internal Medicine

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