Microencapsulated Pomegranate Juice Reduces Metabolic Syndrome (MetS) Criteria in Wistar Rats With MetS Induced With 30% Sucrose

José Antonio Guerrero-Solano; Juan Carlos Cancino-Díaz; Osmar Antonio Jaramillo-Morales; Mirandeli Bautista; Juan Pablo Hernández-Uribe; José Moisés Talamantes-Gómez; Carmen Valadez-Vega; Helen Belefant-Miller; Gabriel Betanzos-Cabrera

doi:10.20944/preprints202409.1728.v1

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preprints.org > biology and life sciences > food science and technology > doi: 10.20944/preprints202409.1728.v1

Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Microencapsulated Pomegranate Juice Reduces Metabolic Syndrome (MetS) Criteria in Wistar Rats With MetS Induced With 30% Sucrose

José Antonio Guerrero-Solano

Juan Carlos Cancino-Díaz

Osmar Antonio Jaramillo-Morales

Mirandeli Bautista

Juan Pablo Hernández-Uribe

José Moisés Talamantes-Gómez

Carmen Valadez-Vega

Helen Belefant-Miller

Gabriel Betanzos-Cabrera

Version 1 : Received: 20 September 2024 / Approved: 23 September 2024 / Online: 23 September 2024 (13:11:46 CEST)

How to cite: Guerrero-Solano, J. A.; Cancino-Díaz, J. C.; Jaramillo-Morales, O. A.; Bautista, M.; Hernández-Uribe, J. P.; Talamantes-Gómez, J. M.; Valadez-Vega, C.; Belefant-Miller, H.; Betanzos-Cabrera, G. Microencapsulated Pomegranate Juice Reduces Metabolic Syndrome (MetS) Criteria in Wistar Rats With MetS Induced With 30% Sucrose. Preprints 2024, 2024091728. https://doi.org/10.20944/preprints202409.1728.v1 Guerrero-Solano, J. A.; Cancino-Díaz, J. C.; Jaramillo-Morales, O. A.; Bautista, M.; Hernández-Uribe, J. P.; Talamantes-Gómez, J. M.; Valadez-Vega, C.; Belefant-Miller, H.; Betanzos-Cabrera, G. Microencapsulated Pomegranate Juice Reduces Metabolic Syndrome (MetS) Criteria in Wistar Rats With MetS Induced With 30% Sucrose. Preprints 2024, 2024091728. https://doi.org/10.20944/preprints202409.1728.v1

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MDPI and ACS Style

Guerrero-Solano, J. A.; Cancino-Díaz, J. C.; Jaramillo-Morales, O. A.; Bautista, M.; Hernández-Uribe, J. P.; Talamantes-Gómez, J. M.; Valadez-Vega, C.; Belefant-Miller, H.; Betanzos-Cabrera, G. Microencapsulated Pomegranate Juice Reduces Metabolic Syndrome (MetS) Criteria in Wistar Rats With MetS Induced With 30% Sucrose. Preprints 2024, 2024091728. https://doi.org/10.20944/preprints202409.1728.v1

APA Style

Guerrero-Solano, J. A., Cancino-Díaz, J. C., Jaramillo-Morales, O. A., Bautista, M., Hernández-Uribe, J. P., Talamantes-Gómez, J. M., Valadez-Vega, C., Belefant-Miller, H., & Betanzos-Cabrera, G. (2024). Microencapsulated Pomegranate Juice Reduces Metabolic Syndrome (MetS) Criteria in Wistar Rats With MetS Induced With 30% Sucrose. Preprints. https://doi.org/10.20944/preprints202409.1728.v1

Chicago/Turabian Style

Guerrero-Solano, J. A., Helen Belefant-Miller and Gabriel Betanzos-Cabrera. 2024 "Microencapsulated Pomegranate Juice Reduces Metabolic Syndrome (MetS) Criteria in Wistar Rats With MetS Induced With 30% Sucrose" Preprints. https://doi.org/10.20944/preprints202409.1728.v1

Abstract

Pomegranate juice possesses therapeutic properties against metabolic syndrome. Microencapsulation of pomegranate juice (MPJ) may extend its shelf life; however, further research is necessary to ascertain its comparative efficacy with fresh juice. This work evaluated the effect of (MPJ) in an animal model with induced metabolic syndrome (MetS). Male Wistar rats were induced-MetS by administering 30% sucrose orally for 22 weeks. Once MetS was verified in the animals, 7 groups were formed as follows: control (Ctrl); MetS, MetS+Placebo; Ctrl+MPJ; MetS+MPJ1 600, MetS+MPJ2 1800, and MetS+MPJ3 2900 mg/kg. Systolic and diastolic blood pressure, glucose, triglycerides, and total HDL-c levels in the MetS+MPJ groups improved significantly (p < 0.05) vs. the MetS group at the end of the study. Microencapsulation maintained the anti-metabolic syndrome properties of pomegranate juice and could be used to control metabolic syndrome.

Keywords

Metabolic syndrome; Microencapsulated pomegranate juice; Cardiovascular diseases; Punica granatum; Biochemical markers

Subject

Biology and Life Sciences, Food Science and Technology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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