Preprint Article Version 1 This version is not peer-reviewed

Vitamin D’s Essential Role from Natural Sources in Preventing Rhinosinusitis, Nasopharyngitis, and Otitis Media: Ensuring Optimal Care in Patients with Behavioral Disorders

Version 1 : Received: 23 September 2024 / Approved: 24 September 2024 / Online: 25 September 2024 (04:18:04 CEST)

How to cite: Manole, F.; Manole, A.; Ghitea, T. C. Vitamin D’s Essential Role from Natural Sources in Preventing Rhinosinusitis, Nasopharyngitis, and Otitis Media: Ensuring Optimal Care in Patients with Behavioral Disorders. Preprints 2024, 2024091929. https://doi.org/10.20944/preprints202409.1929.v1 Manole, F.; Manole, A.; Ghitea, T. C. Vitamin D’s Essential Role from Natural Sources in Preventing Rhinosinusitis, Nasopharyngitis, and Otitis Media: Ensuring Optimal Care in Patients with Behavioral Disorders. Preprints 2024, 2024091929. https://doi.org/10.20944/preprints202409.1929.v1

Abstract

Background/Objective: Adequate serum vitamin D levels are essential for overall health, particularly in preventing oropharyngeal infections. This study aims to explore the relationship between serum vitamin D (25(OH)D3) levels and the prevalence of oropharyngeal diseases—specifically rhinosinusitis, otitis media, and nasopharyngitis—in patients at a private specialist medical clinic. Materials and Methods: The study involved 311 patients with an average age of 15.96±15.06 years. Statistical analyses, including Student's t-test and chi-square test, were conducted to evaluate the significance of the findings. Results: Nasopharyngitis was highly prevalent, affecting 83.27% of participants, with higher recurrence rates in those with lower vitamin D levels (p=0.001). Otitis media was present in 53.37% of cases, while rhinosinusitis was less common and more frequently associated with higher vitamin D levels. Patients with behavioral disorders had significantly higher mean vitamin D levels (34.82 ng/mL ±11.85) compared to those without (28.49 ng/mL ±14.37) (p=0.001). Conclusion: Lower serum vitamin D levels are associated with an increased incidence of oropharyngeal diseases. This study highlights the importance of maintaining optimal vitamin D levels for pediatric health and suggests that higher vitamin D levels may reduce the risk of oropharyngeal infections.

Keywords

behavior disorders; nasopharyngitis; otitis media; rhinosinusitis; vitamin D

Subject

Medicine and Pharmacology, Pediatrics, Perinatology and Child Health

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