Version 1
: Received: 19 September 2024 / Approved: 25 September 2024 / Online: 25 September 2024 (08:52:06 CEST)
How to cite:
Ishida, H.; Manrai, M.; Egashira, H.; Nonaka, M.; Hiruta, N.; Watanabe, R.; Takashima, A. Cervical Mesonephric Adenocarcinoma Treated with Neoadjuvant Chemotherapy. A Case Report and a Literature Review. Preprints2024, 2024091967. https://doi.org/10.20944/preprints202409.1967.v1
Ishida, H.; Manrai, M.; Egashira, H.; Nonaka, M.; Hiruta, N.; Watanabe, R.; Takashima, A. Cervical Mesonephric Adenocarcinoma Treated with Neoadjuvant Chemotherapy. A Case Report and a Literature Review. Preprints 2024, 2024091967. https://doi.org/10.20944/preprints202409.1967.v1
Ishida, H.; Manrai, M.; Egashira, H.; Nonaka, M.; Hiruta, N.; Watanabe, R.; Takashima, A. Cervical Mesonephric Adenocarcinoma Treated with Neoadjuvant Chemotherapy. A Case Report and a Literature Review. Preprints2024, 2024091967. https://doi.org/10.20944/preprints202409.1967.v1
APA Style
Ishida, H., Manrai, M., Egashira, H., Nonaka, M., Hiruta, N., Watanabe, R., & Takashima, A. (2024). Cervical Mesonephric Adenocarcinoma Treated with Neoadjuvant Chemotherapy. A Case Report and a Literature Review. Preprints. https://doi.org/10.20944/preprints202409.1967.v1
Chicago/Turabian Style
Ishida, H., Reiko Watanabe and Akiko Takashima. 2024 "Cervical Mesonephric Adenocarcinoma Treated with Neoadjuvant Chemotherapy. A Case Report and a Literature Review" Preprints. https://doi.org/10.20944/preprints202409.1967.v1
Abstract
Cervical mesonephric ductal adenocarcinoma (MA) is a HPV-independent adenocarcinoma that originates from remnants of the wolffian duct in the male reproductive system during fetal development and occurs in middle-aged women. MA is a rare disease that accounts for less than 1% of all cervical adenocarcinomas. We report a case of MA in which abdominal radical hysterectomy(ARH) was performed after neoadjuvant chemotherapy (NAC). The patient was a 66-year-old woman with abnormal genital bleeding. A colposcopy examination revealed macroscopic invasive cancer. A pelvic MRI scan revealed a 53 × 26 mm tumor in the cervix, and the histological diagnosis of the cervix was endometrioid carcinoma, with the diagnosis being cervical adenocarcinoma cT1b3N0M0. One course of NAC with paclitaxel-carboplatin (PC) was administered to shrink the tumor and stop the bleeding, and ARH was performed. Postoperative histopathological diagnosis was MA. The surgical margins of the resected specimen were negative, and NAC had been effective, so the patient underwent five courses of PC therapy after surgery. There has been no recurrence 12 months after surgery. There is no established standard treatment, but there are reports that PC therapy is effective. It is necessary to search for effective treatments by following up and accumulating further cases.
Medicine and Pharmacology, Obstetrics and Gynaecology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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