PreprintArticleVersion 1This version is not peer-reviewed
Comparison of Three Different IBD Vaccination Protocols in Broiler Chickens – Efficacy, Serological Baselines and Histopathological Lesions in the Bursa of Fabricii
Version 1
: Received: 29 September 2024 / Approved: 30 September 2024 / Online: 30 September 2024 (12:42:39 CEST)
How to cite:
Śmiałek, M.; Kowalczyk, J.; Gesek, M. Comparison of Three Different IBD Vaccination Protocols in Broiler Chickens – Efficacy, Serological Baselines and Histopathological Lesions in the Bursa of Fabricii. Preprints2024, 2024092381. https://doi.org/10.20944/preprints202409.2381.v1
Śmiałek, M.; Kowalczyk, J.; Gesek, M. Comparison of Three Different IBD Vaccination Protocols in Broiler Chickens – Efficacy, Serological Baselines and Histopathological Lesions in the Bursa of Fabricii. Preprints 2024, 2024092381. https://doi.org/10.20944/preprints202409.2381.v1
Śmiałek, M.; Kowalczyk, J.; Gesek, M. Comparison of Three Different IBD Vaccination Protocols in Broiler Chickens – Efficacy, Serological Baselines and Histopathological Lesions in the Bursa of Fabricii. Preprints2024, 2024092381. https://doi.org/10.20944/preprints202409.2381.v1
APA Style
Śmiałek, M., Kowalczyk, J., & Gesek, M. (2024). Comparison of Three Different IBD Vaccination Protocols in Broiler Chickens – Efficacy, Serological Baselines and Histopathological Lesions in the Bursa of Fabricii. Preprints. https://doi.org/10.20944/preprints202409.2381.v1
Chicago/Turabian Style
Śmiałek, M., Joanna Kowalczyk and Michal Gesek. 2024 "Comparison of Three Different IBD Vaccination Protocols in Broiler Chickens – Efficacy, Serological Baselines and Histopathological Lesions in the Bursa of Fabricii" Preprints. https://doi.org/10.20944/preprints202409.2381.v1
Abstract
Background: IBD is a highly infectious disease of chickens found in all latitudes, due to the very high IBDV resistance to environmental conditions and commonly used disinfectants. Methods: The study was conducted to evaluate 3 IBD vaccination protocols in broiler chickens, in terms of their effectiveness (clinical observations and production performance of the flock), estimation of serological baseline values (with the use of two different commercial ELISA kits), and the degree of progression of BF lesions (histopathological lesion score - HLS) after vaccination with: (I) single vaccination using intermediate plus vaccine; (II) double vaccination with intermediate vaccine; (III) double vaccination with intermediate plus vaccine. Results: Birds on farms vaccinated with protocol II were characterized by the lowest antibody titers in both ELISA tests, and the lowest average HLS. Highest IDEXX titers were obtained in birds vaccinated with protocol III, while in the BIOCHEK test the highest titers were obtained for birds vaccinated with protocol I. Protocols I and III were characterized by similar HLS. Birds vaccinated with protocols I and III had higher immune uniformity. Conclusions: The estimated serological baseline values and the degree of HLS presents a clear picture of differences between different vaccination protocols and allows their adaptation for different farms depending on the current IBD epidemiological situation.
Keywords
Gumboro disease; vaccination; live vaccine; ELISA serological baselines
Subject
Biology and Life Sciences, Animal Science, Veterinary Science and Zoology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
