Version 1
: Received: 2 October 2024 / Approved: 2 October 2024 / Online: 3 October 2024 (11:02:02 CEST)
How to cite:
Vinerbi, E.; Morini, G.; Picozzi, C.; Tofanelli, S. Human Salivary Microbiota Diversity According to Ethnicity, Sex, TRPV1 Variants and Sensitivity to Capsaicin. Preprints2024, 2024100184. https://doi.org/10.20944/preprints202410.0184.v1
Vinerbi, E.; Morini, G.; Picozzi, C.; Tofanelli, S. Human Salivary Microbiota Diversity According to Ethnicity, Sex, TRPV1 Variants and Sensitivity to Capsaicin. Preprints 2024, 2024100184. https://doi.org/10.20944/preprints202410.0184.v1
Vinerbi, E.; Morini, G.; Picozzi, C.; Tofanelli, S. Human Salivary Microbiota Diversity According to Ethnicity, Sex, TRPV1 Variants and Sensitivity to Capsaicin. Preprints2024, 2024100184. https://doi.org/10.20944/preprints202410.0184.v1
APA Style
Vinerbi, E., Morini, G., Picozzi, C., & Tofanelli, S. (2024). Human Salivary Microbiota Diversity According to Ethnicity, Sex, TRPV1 Variants and Sensitivity to Capsaicin. Preprints. https://doi.org/10.20944/preprints202410.0184.v1
Chicago/Turabian Style
Vinerbi, E., Claudia Picozzi and Sergio Tofanelli. 2024 "Human Salivary Microbiota Diversity According to Ethnicity, Sex, TRPV1 Variants and Sensitivity to Capsaicin" Preprints. https://doi.org/10.20944/preprints202410.0184.v1
Abstract
The salivary microbiota of Italian and sub-Saharan African individuals was investigated using Nanopore Sequencing Technology (ONT- Oxford Nanopore Technologies). We detected variations in community composition in relation to endogenous (ethnicity, sex and diplotypic variants of the TRPV1 gene) and exogenous (sensitivity to capsaicin) factors. The results showed that, Prevotella, Haemophilus, Neisseria, Streptococcus, Veillonella and Rothia, are the most abundant genera, in accordance with the literature. However, alpha diversity and frequency spectra differed significantly between DNA pools. The microbiota in African, male, TRPV1 bb/ab diplotype and capsaicin low sensitive DNA pools was more diverse than Italian, female, TRPV1 aa diplotype and capsaicin high sensitive DNA pools. Relative abundance differed at phylum, genus and species level.
Keywords
Human microbiota; salivary microbiota; ethnicity, sex, TRPV1 gene; capsaicin
Subject
Biology and Life Sciences, Biology and Biotechnology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
