Preprint Review Version 1 This version is not peer-reviewed

Myval Transcatheter Heart Valve: The Future of Transcatheter Valve Replacement and Significance in Current Timeline

Version 1 : Received: 2 October 2024 / Approved: 2 October 2024 / Online: 2 October 2024 (14:49:09 CEST)

How to cite: Kilic, T.; Coskun, S.; Mirzaminidov, D.; Yilmaz, I.; Yavuz, S.; Sahin, T. Myval Transcatheter Heart Valve: The Future of Transcatheter Valve Replacement and Significance in Current Timeline. Preprints 2024, 2024100199. https://doi.org/10.20944/preprints202410.0199.v1 Kilic, T.; Coskun, S.; Mirzaminidov, D.; Yilmaz, I.; Yavuz, S.; Sahin, T. Myval Transcatheter Heart Valve: The Future of Transcatheter Valve Replacement and Significance in Current Timeline. Preprints 2024, 2024100199. https://doi.org/10.20944/preprints202410.0199.v1

Abstract

The Myval is a balloon-expandable transcatheter heart valve (THV) devel-oped by Meril Life Sciences Pvt. Ltd. that has innovative operator-friendly de-sign which aids to improve deliverability and features precise deployment. Vari-ous clinical studies demonstrate its effectiveness and safety, making it a promis-ing choice in valvular interventions. Myval has been successfully utilized as a transcatheter aortic valve implanta-tion (TAVI) device in cases with conduction disturbances, bicuspid aortic valve anatomy, non-calcified aortic regurgitation, dysfunctional stenosed right ventric-ular outflow tract (RVOT) conduits, pulmonary valve replacement, mitral valve replacement, Vave-in-valve and Valve-in-ring implantation procedures. Myval’s diverse sizes are also of key importance in complex cases of large and complex annuli anatomy. Further long-term studies are needed to consolidate these results. Its introduction signifies a significant advancement in cardiology, aiming to enhance patient outcomes and quality of life. In the present review, we provide an update on new-generation Myval THVs and review the available clinical data published till date with an emphasis on diverse use in specific clinical scenarios.

Keywords

Myval; Safety; transcatheter aortic valve implantation; transcatheter heart valve; valve-in-valve implantation

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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