Preprint Article Version 1 This version is not peer-reviewed

Tackling the Challenge of Visceral Leishmaniasis: A Severe Threat to Public Health

Version 1 : Received: 7 October 2024 / Approved: 7 October 2024 / Online: 8 October 2024 (07:16:46 CEST)

How to cite: Mohan, A.; Naisam, S.; Sreekumar, N. Tackling the Challenge of Visceral Leishmaniasis: A Severe Threat to Public Health. Preprints 2024, 2024100513. https://doi.org/10.20944/preprints202410.0513.v1 Mohan, A.; Naisam, S.; Sreekumar, N. Tackling the Challenge of Visceral Leishmaniasis: A Severe Threat to Public Health. Preprints 2024, 2024100513. https://doi.org/10.20944/preprints202410.0513.v1

Abstract

Visceral leishmaniasis (VL), or kala-azar, is a severe and potentially fatal form of leishmaniasis, a disease classified under Neglected Tropical Diseases (NTDs). VL primarily affects the internal organs, with symptoms ranging from chronic fever and weight loss to hepatosplenomegaly and anemia. The disease is transmitted by sandflies, with Leishmania donovani and Leishmania infantum being the primary pathogens. Despite various treatment options like liposomal amphotericin B and miltefosine, challenges remain due to drug toxicity, high costs, and limited availability. Alternative therapeutic approaches, particularly those involving phytocompounds, offer promising potential for overcoming these limitations and improving outcomes for affected populations.

Keywords

visceral leishmaniasis; leishmania donovani; neglected tropical diseases; sandfly transmission; phytocompounds

Subject

Public Health and Healthcare, Public Health and Health Services

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.