PreprintCase ReportVersion 1This version is not peer-reviewed
A Case of B-Cell Lymphoblastic Lymphoma Presenting with an Isolated Epidural Mass Treated Successfully with Radiotherapy Followed by UKALL Chemotherapy Protocol
Version 1
: Received: 10 October 2024 / Approved: 11 October 2024 / Online: 12 October 2024 (07:33:23 CEST)
How to cite:
Alzahrani, M. A Case of B-Cell Lymphoblastic Lymphoma Presenting with an Isolated Epidural Mass Treated Successfully with Radiotherapy Followed by UKALL Chemotherapy Protocol. Preprints2024, 2024100859. https://doi.org/10.20944/preprints202410.0859.v1
Alzahrani, M. A Case of B-Cell Lymphoblastic Lymphoma Presenting with an Isolated Epidural Mass Treated Successfully with Radiotherapy Followed by UKALL Chemotherapy Protocol. Preprints 2024, 2024100859. https://doi.org/10.20944/preprints202410.0859.v1
Alzahrani, M. A Case of B-Cell Lymphoblastic Lymphoma Presenting with an Isolated Epidural Mass Treated Successfully with Radiotherapy Followed by UKALL Chemotherapy Protocol. Preprints2024, 2024100859. https://doi.org/10.20944/preprints202410.0859.v1
APA Style
Alzahrani, M. (2024). A Case of B-Cell Lymphoblastic Lymphoma Presenting with an Isolated Epidural Mass Treated Successfully with Radiotherapy Followed by UKALL Chemotherapy Protocol. Preprints. https://doi.org/10.20944/preprints202410.0859.v1
Chicago/Turabian Style
Alzahrani, M. 2024 "A Case of B-Cell Lymphoblastic Lymphoma Presenting with an Isolated Epidural Mass Treated Successfully with Radiotherapy Followed by UKALL Chemotherapy Protocol" Preprints. https://doi.org/10.20944/preprints202410.0859.v1
Abstract
B-cell lymphoblastic lymphoma (B-LBL) is an aggressive type of non-Hodgkin lymphoma that usually involves lymph nodes, skin and soft tissue. Bone marrow and peripheral blood are normally spared from involvement by the disease. B-LBL typically forms sold masses that have similar pathologic and immunophenotypic features of the liquid counterpart, B-cell acute lymphoblastic leukemia (B-ALL). Presentation of B-LBL with a solitary epidural mass at the cervical spine is very rare and the optimal treatment of such cases is unknown. Most of the literature on management of B-LBL comes from small case series, pediatric patients, or as part of retrospective data that combine B-LBL with B-ALL cases.
The case presented herein, showed a unique presentation that was then treated with three modalities, namely, surgical resection, radiotherapy, and consolidation with systemic chemotherapy adopted from United Kingdom acute lymphoblastic leukemia (UKALL) protocol.
The patient attained a complete response following the planned treatment and is still in remission five years from the time of his initial diagnosis.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
