Preprint Article Version 1 This version is not peer-reviewed

Comparison of Clinical and Morpho-anatomical Characteristics in Aneurysmal Degenerated and Non-aneurysmal Insufficient Great Saphenous Vein

Version 1 : Received: 11 October 2024 / Approved: 12 October 2024 / Online: 12 October 2024 (08:16:52 CEST)

How to cite: Stef, D. G.; Patrascu, R. Comparison of Clinical and Morpho-anatomical Characteristics in Aneurysmal Degenerated and Non-aneurysmal Insufficient Great Saphenous Vein. Preprints 2024, 2024100962. https://doi.org/10.20944/preprints202410.0962.v1 Stef, D. G.; Patrascu, R. Comparison of Clinical and Morpho-anatomical Characteristics in Aneurysmal Degenerated and Non-aneurysmal Insufficient Great Saphenous Vein. Preprints 2024, 2024100962. https://doi.org/10.20944/preprints202410.0962.v1

Abstract

Background: Saphenous vein degeneration is associated with significant morphological changes. This study compares the clinical and morpho-anatomical characteristics between patients with aneurysmal and non-aneurysmal insufficient great saphenous vein (GSV). Methods: A retrospective observational analysis was conducted on 75 patients with chronic venous disease. Patients were divided into Group A (n=17, GSV diameter ≥1.2 cm) and Group B (n=58, GSV diameter 0.6-1.2 cm). Clinical data and morpho-anatomical features were assessed using ultrasonography and histopathological examination. Results: Group A had significantly larger GSV diameter (1.4 ± 0.2 cm vs. 0.7 ± 0.1 cm, p < 0.001) and wall thickness (0.4 ± 0.1 cm vs. 0.2 ± 0.1 cm, p < 0.001). Elastic fiber fragmentation was more severe in Group A (55% vs. 29%, p < 0.01). Group A also had a higher mean BMI (31.4 ± 4.5 kg/m² vs. 27.4 ± 4.0 kg/m², p = 0.007) and longer hospitalization (2.1 ± 0.6 days vs. 1.5 ± 0.6 days, p = 0.0023). Conclusions: Aneurysmal degeneration is linked to more severe clinical and morphoanatomical changes, indicating a need for closer monitoring and more aggressive treatment strategies.

Keywords

saphenous vein degeneration; vein insufficiency; morphoanatomical features; vascular pathology

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.