Preprint Article Version 1 This version is not peer-reviewed

Assessing the Efficacy and Safety of Extubation Protocols in the Intensive Care Unit Following Transoral Robotic Surgery for Obstructive Sleep Apnea Syndrome: A Retrospective Cohort Study

Andreaserena Recchia
* ,
Marco Cascella
* ,
Massimiliano Copetti
,
Alessio Barile
,
Elena Giovanna Bignami
,
Aurelio D’Ecclesia
,
Antonio Izzi
,
Aldo Manuali
,
Vincenzo Marchello
,
Giuseppe Mincolelli
,
Alfredo Del Gaudio
Version 1 : Received: 17 October 2024 / Approved: 18 October 2024 / Online: 18 October 2024 (13:23:49 CEST)

How to cite: Recchia, A.; Cascella, M.; Copetti, M.; Barile, A.; Bignami, E. G.; D’Ecclesia, A.; Izzi, A.; Manuali, A.; Marchello, V.; Mincolelli, G.; Del Gaudio, A. Assessing the Efficacy and Safety of Extubation Protocols in the Intensive Care Unit Following Transoral Robotic Surgery for Obstructive Sleep Apnea Syndrome: A Retrospective Cohort Study. Preprints 2024, 2024101501. https://doi.org/10.20944/preprints202410.1501.v1 Recchia, A.; Cascella, M.; Copetti, M.; Barile, A.; Bignami, E. G.; D’Ecclesia, A.; Izzi, A.; Manuali, A.; Marchello, V.; Mincolelli, G.; Del Gaudio, A. Assessing the Efficacy and Safety of Extubation Protocols in the Intensive Care Unit Following Transoral Robotic Surgery for Obstructive Sleep Apnea Syndrome: A Retrospective Cohort Study. Preprints 2024, 2024101501. https://doi.org/10.20944/preprints202410.1501.v1

Abstract

Background: There is a notable lack of protocols addressing extubation techniques in transoral robotic surgery (TORS) for obstructive sleep apnea (OSA). Methods. This retrospective cohort study enrolled patients who underwent TORS for OSA between March 2015 and December 2021 and were managed with different extubation approaches. The patients were divided into two groups: high-flow nasal cannula (HFNC) therapy and conventional oxygen therapy. The use of an airway exchange catheter (AEC) was investigated. Results: The only application of HFNC use versus conventional oxygen therapy led to a statistical reduction of extubation time (p=0.024); length of stay in the intensive care unit (ICU) and the episodes of desaturation below 95% were reduced, but data are non-statically significant. Similarly, the application of an AEC led to a reduction of extubation time in hours (p=0.008) and length of stay in the ICU (p=0.024). Conclusions: In patients with OSA who underwent TORS, the use of HFNC, with or without an AEC, resulted in a significant reduction in extubation time without major adverse events. Additionally, HFNC utilization may decrease desaturation episodes during extubation. Based on the findings of this preliminary investigation, the combination of HFNC and AEC emerges as a promising strategy for enhancing the safety and efficacy of extubation protocols in this patient population.

Keywords

obstructive sleep apnea; anesthesia; safety; transoral robotic surgery

Subject

Medicine and Pharmacology, Anesthesiology and Pain Medicine

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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