Preprint Article Version 1 This version is not peer-reviewed

Evaluation of the Effects of Age, Gender and Dexpanthenol Containing Skincare on the Facial and Body Skin Microbiome

Version 1 : Received: 25 October 2024 / Approved: 28 October 2024 / Online: 28 October 2024 (07:01:08 CET)

How to cite: Qaizar, Z.; Salvo, R. D.; Bieri, G.; Unbereit, K.; Montgomery, S.; Peltier, E. Evaluation of the Effects of Age, Gender and Dexpanthenol Containing Skincare on the Facial and Body Skin Microbiome. Preprints 2024, 2024102139. https://doi.org/10.20944/preprints202410.2139.v1 Qaizar, Z.; Salvo, R. D.; Bieri, G.; Unbereit, K.; Montgomery, S.; Peltier, E. Evaluation of the Effects of Age, Gender and Dexpanthenol Containing Skincare on the Facial and Body Skin Microbiome. Preprints 2024, 2024102139. https://doi.org/10.20944/preprints202410.2139.v1

Abstract

Given the pivotal role played by the microbiome in skin health it is important to understand how its composition varies with age, gender and body site, and regular use of topical products. Four studies have been carried out to determine the effects of long term (4 week) use of different dexpanthenol containing topical products on the skin microbiome of a varied population with cosmetically dry skin. Skin microbiome composition was assessed before and after product usage. No significant changes in microbiome richness or diversity were found for the individual test products, however meta-analysis of the combined dataset did show changes in microbiome composition as a function of subject sex, age and body site. The work presented here demonstrates how the use of carefully formulated topical products on skin, when used in a way which is representative of real life usage conditions, can respect the microbial diversity present on skin across a widely varied study population.

Keywords

Microbiome; Topical products; Skin health.; dry skin; dexpanthenol; repair; xerosis

Subject

Medicine and Pharmacology, Anatomy and Physiology

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